SCHEMBL9623934

SCHEMBL9623934

Cc1cc(Cl)c(C)cc1Cl.Cc1cc(Cl)cc(C)c1Cl

nearest known ligand 0.48

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
CYP3A4 P08684 3/20 0.48
CHRM1 P11229 1/20 0.48
ALOX15 P16050 1/20 0.48
MAOA P21397 1/20 0.48
TBXA2R P21731 1/20 0.48
ADRA1A P35348 1/20 0.48
HTR2B P41595 1/20 0.48
CD44 P16070 1/20 0.46
RAPGEF4 Q8WZA2 5/20 0.45
ALDH1A1 P00352 3/20 0.43
GRIN2D O15399 1/20 0.38
GRIN3B O60391 1/20 0.38
GRIN1 Q05586 1/20 0.38
GRIN2A Q12879 1/20 0.38
GRIN2B Q13224 1/20 0.38
GRIN2C Q14957 1/20 0.38
GRIN3A Q8TCU5 1/20 0.38
SIRT1 Q96EB6 1/20 0.38
TSHR P16473 3/20 0.37
LMNA P02545 1/20 0.37

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL765882 0.88 CYP3A4 (0.58) CYP3A4CHRM1ALOX15MAOATBXA2R
SCHEMBL120848 0.82 CD44 (0.61) CYP3A4CHRM1ALOX15MAOATBXA2R
SCHEMBL29351204 0.80 ALDH1A1 (0.61) CYP3A4CHRM1ALOX15MAOATBXA2R
SCHEMBL180195 0.80 ALDH1A1 (0.61) CYP3A4CHRM1ALOX15MAOATBXA2R
Water SCHEMBL29026586 0.78 CD44 (0.58) CYP3A4CHRM1ALOX15MAOATBXA2R
SCHEMBL2219302 0.76 CD44 (0.55) CYP3A4CHRM1ALOX15MAOATBXA2R
SCHEMBL168826 0.76 CD44 (0.55) CYP3A4CHRM1ALOX15MAOATBXA2R
SCHEMBL8261003 0.72 CD44 (0.58) CYP3A4CHRM1ALOX15MAOATBXA2R
SCHEMBL13176877 0.71 CD44 (0.50) CYP3A4CHRM1ALOX15MAOATBXA2R
SCHEMBL31519176 0.71 CYP3A4 (0.59) CYP3A4CHRM1ALOX15MAOATBXA2R

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-5138031-A LINEAR AND BRANCHED POLY-P-ARYLENE SULFIDE SUBSTANTIALLY FREE FROM DEFECT STRUCTURES HAVING PLURAL ABSORPTION MAXIMA BAYER AKTIENGESELLSCHAFT (DE) 1992-08-11 US disclosed
EP-0373364-A2 Hardly structurally faulty linear or branched poly-p-arylene sulfide, process for its preparation and its use BAYER AG (DE) 1990-06-20 EP disclosed