Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | DNM1 | Q05193 | 6/20 | 0.43 |
| ▸ | EPHX2 | P34913 | 2/20 | 0.39 |
| ▸ | S1PR2 | O95136 | 1/20 | 0.39 |
| ▸ | S1PR1 | P21453 | 1/20 | 0.39 |
| ▸ | S1PR3 | Q99500 | 1/20 | 0.39 |
| ▸ | S1PR5 | Q9H228 | 1/20 | 0.39 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.39 |
| ▸ | GGPS1 | O95749 | 3/20 | 0.37 |
| ▸ | CES2 | O00748 | 3/20 | 0.37 |
| ▸ | CES1 | P23141 | 3/20 | 0.37 |
| ▸ | KDM5A | P29375 | 1/20 | 0.37 |
| ▸ | KDM4C | Q9H3R0 | 1/20 | 0.37 |
| ▸ | PHF8 | Q9UPP1 | 1/20 | 0.37 |
| ▸ | GPR84 | Q9NQS5 | 2/20 | 0.35 |
| ▸ | PPARG | P37231 | 2/20 | 0.35 |
| ▸ | PPARD | Q03181 | 2/20 | 0.35 |
| ▸ | PPARA | Q07869 | 2/20 | 0.35 |
| ▸ | TSHR | P16473 | 1/20 | 0.35 |
| ▸ | SLC22A6 | Q4U2R8 | 1/20 | 0.35 |
| ▸ | SLC22A8 | Q8TCC7 | 1/20 | 0.35 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL3310787 | 0.92 | ALDH1A1 (0.41) | DNM1EPHX2ALDH1A1CES2CES1 | |
| SCHEMBL9792595 | 0.92 | ALDH1A1 (0.33) | ALDH1A1TSHR | |
| SCHEMBL9846342 | 0.83 | ALDH1A1 (0.34) | ALDH1A1TSHR | |
| SCHEMBL5253602 | 0.81 | CA12 (0.43) | ALDH1A1CES2CES1KDM5AKDM4C | |
| SCHEMBL23161586 | 0.77 | EPHX2 (0.54) | DNM1EPHX2S1PR2S1PR1S1PR3 | |
| SCHEMBL19570764 | 0.77 | CA12 (0.48) | DNM1EPHX2S1PR2S1PR1S1PR3 | |
| SCHEMBL31310487 | 0.77 | EPHX2 (0.54) | DNM1EPHX2S1PR2S1PR1S1PR3 | |
| SCHEMBL25166796 | 0.76 | DNM1 (0.34) | DNM1EPHX2S1PR2S1PR1S1PR3 | |
| SCHEMBL9781705 | 0.75 | DNM1 (0.46) | DNM1EPHX2S1PR2S1PR1S1PR3 | |
| SCHEMBL9781749 | 0.75 | DNM1 (0.46) | DNM1EPHX2S1PR2S1PR1S1PR3 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 4 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-5079206-A | For obtaining high molecular weight/narrow distribution addition homo- or copolymers by controlled bulk polymerization; silcon, germanium or tin organic compounds; cocatalysts | IMPERIAL CHEMICAL INDUSTRIES PLC (GB) | 1992-01-07 | — | — | US | disclosed |
| EP-0413464-A2 | Catalysts | IMPERIAL CHEMICAL INDUSTRIES PLC (GB) | 1991-02-20 | — | — | EP | disclosed |
| EP-0413465-A2 | Catalysts | IMPERIAL CHEMICAL INDUSTRIES PLC (GB) | 1991-02-20 | — | — | EP | disclosed |
| EP-0405785-A2 | Catalysts | IMPERIAL CHEMICAL INDUSTRIES PLC (GB) | 1991-01-02 | — | — | EP | disclosed |