Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | KDM4E | B2RXH2 | 5/20 | 0.48 |
| ▸ | MAPT | P10636 | 4/20 | 0.46 |
| ▸ | LMNA | P02545 | 2/20 | 0.46 |
| ▸ | NPC1 | O15118 | 1/20 | 0.45 |
| ▸ | CYP2C9 | P11712 | 1/20 | 0.45 |
| ▸ | RAB9A | P51151 | 1/20 | 0.45 |
| ▸ | NPSR1 | Q6W5P4 | 1/20 | 0.45 |
| ▸ | FDPS | P14324 | 3/20 | 0.45 |
| ▸ | ALDH1A1 | P00352 | 4/20 | 0.44 |
| ▸ | TDP1 | Q9NUW8 | 3/20 | 0.44 |
| ▸ | GAA | P10253 | 1/20 | 0.44 |
| ▸ | POLB | P06746 | 2/20 | 0.43 |
| ▸ | PRKCE | Q02156 | 1/20 | 0.43 |
| ▸ | PRKCQ | Q04759 | 1/20 | 0.43 |
| ▸ | PRKCD | Q05655 | 1/20 | 0.43 |
| ▸ | HPGD | P15428 | 1/20 | 0.43 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.43 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.43 |
| ▸ | PPARA | Q07869 | 1/20 | 0.43 |
| ▸ | LTA4H | P09960 | 1/20 | 0.43 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL9534463 | 0.89 | GAA (0.56) | KDM4EMAPTLMNAALDH1A1TDP1 | |
| SCHEMBL8411878 | 0.86 | KDM4E (0.59) | KDM4EMAPTNPC1CYP2C9RAB9A | |
| SCHEMBL8330027 | 0.83 | MAPT (0.62) | KDM4EMAPTLMNACYP2C9NPSR1 | |
| SCHEMBL9170930 | 0.80 | MAPT (0.61) | KDM4EMAPTLMNACYP2C9NPSR1 | |
| SCHEMBL8334220 | 0.79 | KDM4E (0.50) | KDM4EMAPTLMNANPC1CYP2C9 | |
| SCHEMBL8656523 | 0.79 | MAPT (0.52) | KDM4EMAPTLMNANPC1CYP2C9 | |
| SCHEMBL6229506 | 0.78 | MAPT (0.56) | KDM4EMAPTLMNACYP2C9RAB9A | |
| SCHEMBL9623864 | 0.78 | FLT3 (0.46) | KDM4EMAPTLMNACYP2C9RAB9A | |
| SCHEMBL11824995 | 0.78 | ALDH1A1 (0.64) | KDM4EMAPTLMNACYP2C9NPSR1 | |
| SCHEMBL11825001 | 0.78 | ALDH1A1 (0.64) | KDM4EMAPTLMNACYP2C9NPSR1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 8 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0350386-B1 | UNSATURATED DERIVATIVES OF LIPID SOLUBLE BENZAL MALONATES, AND THEIR USE AS UV ABSORBERS IN THE COSMETIC FIELD | L'OREAL (FR) | 1992-04-08 | — | — | EP | claimed |
| EP-0350386-A1 | Unsaturated derivatives of lipid soluble benzal malonates, and their use as UV absorbers in the cosmetic field | L'OREAL (FR) | 1990-01-10 | — | — | EP | claimed |
| EP-0392882-B1 | COSMETIC COMPOSITIONS CONTAINING DIORGANOPOLYSILOXANES WITH A BENZALMALONATE FUNCTION FOR SKIN AND HAIR PROTECTION, AND THEIR USE | L'OREAL (FR) | 1992-10-28 | — | — | EP | disclosed |
| EP-0358584-B1 | DIORGANOPOLYSILOXANES CONTAINING FUNCTIONAL BENZAL MALONATE GROUPS | RHONE-POULENC CHIMIE (FR) | 1992-09-16 | — | — | EP | disclosed |
| EP-0350386-B1 | UNSATURATED DERIVATIVES OF LIPID SOLUBLE BENZAL MALONATES, AND THEIR USE AS UV ABSORBERS IN THE COSMETIC FIELD | L'OREAL (FR) | 1992-04-08 | — | — | EP | disclosed |
| EP-0392882-A1 | Cosmetic compositions containing diorganopolysiloxanes with a benzalmalonate function for skin and hair protection, and their use | L'OREAL (FR) | 1990-10-17 | — | — | EP | disclosed |
| EP-0358584-A1 | Diorganopolysiloxanes containing functional benzal malonate groups | RHONE-POULENC CHIMIE (FR) | 1990-03-14 | — | — | EP | disclosed |
| EP-0350386-A1 | Unsaturated derivatives of lipid soluble benzal malonates, and their use as UV absorbers in the cosmetic field | L'OREAL (FR) | 1990-01-10 | — | — | EP | disclosed |