Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | SHBG | P04278 | 9/20 | 0.64 |
| ▸ | NR3C1 | P04150 | 5/20 | 0.64 |
| ▸ | PGR | P06401 | 4/20 | 0.64 |
| ▸ | ALDH1A1 | P00352 | 3/20 | 0.64 |
| ▸ | ADRA1A | P35348 | 1/20 | 0.64 |
| ▸ | HTR2B | P41595 | 1/20 | 0.64 |
| ▸ | LMNA | P02545 | 8/20 | 0.61 |
| ▸ | SMN1; SMN2 | Q16637 | 5/20 | 0.61 |
| ▸ | TSHR | P16473 | 5/20 | 0.61 |
| ▸ | CYP2C19 | P33261 | 3/20 | 0.61 |
| ▸ | AR | P10275 | 3/20 | 0.61 |
| ▸ | MEN1 | O00255 | 2/20 | 0.61 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.61 |
| ▸ | HIF1A | Q16665 | 2/20 | 0.61 |
| ▸ | THRB | P10828 | 1/20 | 0.61 |
| ▸ | ESR1 | P03372 | 1/20 | 0.61 |
| ▸ | SERPINA6 | P08185 | 7/20 | 0.59 |
| ▸ | BLM | P54132 | 4/20 | 0.59 |
| ▸ | MAPT | P10636 | 2/20 | 0.59 |
| ▸ | CYP17A1 | P05093 | 2/20 | 0.59 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL9624055 | 1.00 | SHBG (0.64) | SHBGNR3C1PGRALDH1A1ADRA1A | |
| SCHEMBL10892430 | 0.89 | SHBG (0.70) | SHBGNR3C1PGRALDH1A1ADRA1A | |
| SCHEMBL10868441 | 0.89 | SHBG (0.70) | SHBGNR3C1PGRALDH1A1ADRA1A | |
| SCHEMBL9347593 | 0.85 | SHBG (0.70) | SHBGNR3C1PGRALDH1A1ADRA1A | |
| SCHEMBL24476211 | 0.82 | SHBG (0.79) | SHBGNR3C1PGRALDH1A1ADRA1A | |
| SCHEMBL8746790 | 0.82 | SHBG (0.79) | SHBGNR3C1PGRALDH1A1ADRA1A | |
| SCHEMBL22920273 | 0.82 | SHBG (0.79) | SHBGNR3C1PGRALDH1A1ADRA1A | |
| SCHEMBL11062192 | 0.82 | SHBG (0.79) | SHBGNR3C1PGRALDH1A1ADRA1A | |
| SCHEMBL8746789 | 0.82 | SHBG (0.79) | SHBGNR3C1PGRALDH1A1ADRA1A | |
| SCHEMBL10867342 | 0.82 | SHBG (0.69) | SHBGNR3C1PGRALDH1A1ADRA1A |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0268400-B1 | STEROIDAL 17ALPHA-SILYL ETHERS AND PROCESS TO CORTICOIDS AND PROGESTERONES | THE UPJOHN COMPANY (US) | 1992-04-29 | — | — | EP | claimed |