Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | SHBG | P04278 | 8/20 | 0.70 |
| ▸ | LMNA | P02545 | 8/20 | 0.70 |
| ▸ | NR3C1 | P04150 | 5/20 | 0.70 |
| ▸ | SMN1; SMN2 | Q16637 | 5/20 | 0.70 |
| ▸ | TSHR | P16473 | 5/20 | 0.70 |
| ▸ | PGR | P06401 | 4/20 | 0.70 |
| ▸ | CYP2C19 | P33261 | 3/20 | 0.70 |
| ▸ | AR | P10275 | 3/20 | 0.70 |
| ▸ | MEN1 | O00255 | 2/20 | 0.70 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.70 |
| ▸ | HIF1A | Q16665 | 2/20 | 0.70 |
| ▸ | THRB | P10828 | 1/20 | 0.70 |
| ▸ | ESR1 | P03372 | 1/20 | 0.70 |
| ▸ | ALDH1A1 | P00352 | 3/20 | 0.64 |
| ▸ | ADRA1A | P35348 | 1/20 | 0.64 |
| ▸ | HTR2B | P41595 | 1/20 | 0.64 |
| ▸ | SERPINA6 | P08185 | 7/20 | 0.59 |
| ▸ | BLM | P54132 | 4/20 | 0.59 |
| ▸ | MAPT | P10636 | 2/20 | 0.59 |
| ▸ | ADORA3 | P0DMS8 | 1/20 | 0.59 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL10892430 | 1.00 | SHBG (0.70) | SHBGLMNANR3C1SMN1; SMN2TSHR | |
| SCHEMBL9624053 | 0.89 | SHBG (0.64) | SHBGLMNANR3C1SMN1; SMN2TSHR | |
| SCHEMBL9624055 | 0.89 | SHBG (0.64) | SHBGLMNANR3C1SMN1; SMN2TSHR | |
| SCHEMBL9347593 | 0.85 | SHBG (0.70) | SHBGLMNANR3C1SMN1; SMN2TSHR | |
| SCHEMBL10444758 | 0.85 | NR3C1 (0.50) | SHBGLMNANR3C1SMN1; SMN2TSHR | |
| SCHEMBL15079251 | 0.85 | NR3C1 (0.50) | SHBGLMNANR3C1SMN1; SMN2TSHR | |
| SCHEMBL16387349 | 0.84 | HIF1A (0.61) | SHBGLMNANR3C1SMN1; SMN2TSHR | |
| SCHEMBL15079260 | 0.84 | HIF1A (0.61) | SHBGLMNANR3C1SMN1; SMN2TSHR | |
| Ethisterone SCHEMBL16864523 | 0.82 | LMNA (1.00) | SHBGLMNANR3C1SMN1; SMN2TSHR | |
| Ethisterone SCHEMBL16691330 | 0.82 | LMNA (1.00) | SHBGLMNANR3C1SMN1; SMN2TSHR |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 5 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-4567001-A | 16-Methylene-17α-hydroxy-progesterones | THE UPJOHN COMPANY (US) | 1986-01-28 | — | — | US | claimed |
| US-4588529-A | Mercury removal process | THE UPJOHN COMPANY (US) | 1986-05-13 | — | — | US | disclosed |
| EP-0179496-A1 | 16-Sulfinylmethyl-steroids, their preparation and use | THE UPJOHN COMPANY (US) | 1986-04-30 | — | — | EP | disclosed |
| US-4567001-A | 16-Methylene-17α-hydroxy-progesterones | THE UPJOHN COMPANY (US) | 1986-01-28 | — | — | US | disclosed |
| EP-0104054-A2 | 16-methylene-steroids and their preparation | THE UPJOHN COMPANY (US) | 1984-03-28 | — | — | EP | disclosed |