Predicted protein targets (top 17)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.59 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.59 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.59 |
| ▸ | PAM | P19021 | 1/20 | 0.58 |
| ▸ | TSHR | P16473 | 1/20 | 0.47 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.46 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.46 |
| ▸ | FFAR1 | O14842 | 1/20 | 0.46 |
| ▸ | CES2 | O00748 | 1/20 | 0.45 |
| ▸ | CES1 | P23141 | 1/20 | 0.45 |
| ▸ | AKR1B1 | P15121 | 1/20 | 0.45 |
| ▸ | LMNA | P02545 | 1/20 | 0.44 |
| ▸ | MGLL | Q99685 | 2/20 | 0.44 |
| ▸ | GAA | P10253 | 1/20 | 0.44 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.44 |
| ▸ | MEN1 | O00255 | 1/20 | 0.43 |
| ▸ | RAB9A | P51151 | 1/20 | 0.43 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL24991262 | 0.83 | ALDH1A1 (0.66) | ALDH1A1MAPK1L3MBTL1PAMTSHR | |
| SCHEMBL27166998 | 0.80 | FFAR1 (0.47) | ALDH1A1MAPK1L3MBTL1TSHRTDP1 | |
| SCHEMBL6535141 | 0.80 | FFAR1 (0.47) | ALDH1A1MAPK1KMT2ATDP1FFAR1 | |
| SCHEMBL10401993 | 0.79 | FFAR1 (0.54) | ALDH1A1MAPK1KMT2AFFAR1LMNA | |
| SCHEMBL10401991 | 0.77 | FFAR1 (0.52) | ALDH1A1MAPK1KMT2AFFAR1LMNA | |
| SCHEMBL1434644 | 0.77 | ALDH1A1 (0.73) | ALDH1A1MAPK1L3MBTL1PAMTSHR | |
| SCHEMBL6535462 | 0.76 | FFAR1 (0.43) | ALDH1A1MAPK1L3MBTL1KMT2ATDP1 | |
| SCHEMBL6248478 | 0.76 | ALDH1A1 (0.52) | ALDH1A1MAPK1L3MBTL1TSHRKMT2A | |
| SCHEMBL361779 | 0.75 | ALDH1A1 (1.00) | ALDH1A1MAPK1L3MBTL1PAMTSHR | |
| SCHEMBL5663575 | 0.75 | ALDH1A1 (0.70) | ALDH1A1MAPK1L3MBTL1PAMTSHR |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0300828-B1 | IODINATED ESTERS | NYCOMED AS (NO) | 1992-03-18 | — | — | EP | disclosed |
| WO-1989000988-A1 | IODINATED ESTERS | NYCOMED AS (NO) | 1989-02-09 | — | — | WO | disclosed |
| EP-0300828-A1 | Iodinated esters | NYCOMED AS (NO) | 1989-01-25 | — | — | EP | disclosed |