Predicted protein targets (top 17)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | FFAR1 | O14842 | 1/20 | 0.47 |
| ▸ | ALDH1A1 | P00352 | 7/20 | 0.44 |
| ▸ | HPGD | P15428 | 1/20 | 0.44 |
| ▸ | NPC1 | O15118 | 2/20 | 0.42 |
| ▸ | RAB9A | P51151 | 2/20 | 0.42 |
| ▸ | MAPT | P10636 | 1/20 | 0.42 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.42 |
| ▸ | MTNR1A | P48039 | 4/20 | 0.42 |
| ▸ | MTNR1B | P49286 | 4/20 | 0.42 |
| ▸ | MAPK1 | P28482 | 2/20 | 0.41 |
| ▸ | L3MBTL1 | Q9Y468 | 2/20 | 0.41 |
| ▸ | ELANE | P08246 | 1/20 | 0.41 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.41 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.40 |
| ▸ | TSHR | P16473 | 1/20 | 0.40 |
| ▸ | HSD17B10 | Q99714 | 1/20 | 0.40 |
| ▸ | TP53 | P04637 | 1/20 | 0.40 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL28145857 | 0.84 | ALDH1A1 (0.49) | FFAR1ALDH1A1HPGDNPC1RAB9A | |
| SCHEMBL16594277 | 0.83 | ALDH1A1 (0.43) | FFAR1ALDH1A1HPGDNPC1RAB9A | |
| SCHEMBL7117061 | 0.82 | ELANE (0.39) | FFAR1ALDH1A1HPGDNPC1RAB9A | |
| SCHEMBL6535141 | 0.81 | FFAR1 (0.47) | FFAR1ALDH1A1HPGDNPC1RAB9A | |
| SCHEMBL6248478 | 0.81 | ALDH1A1 (0.52) | FFAR1ALDH1A1HPGDNPC1RAB9A | |
| SCHEMBL10401993 | 0.80 | FFAR1 (0.54) | FFAR1ALDH1A1HPGDNPC1RAB9A | |
| SCHEMBL9624319 | 0.80 | ALDH1A1 (0.59) | FFAR1ALDH1A1RAB9ASMN1; SMN2MAPK1 | |
| SCHEMBL10401991 | 0.79 | FFAR1 (0.52) | FFAR1ALDH1A1HPGDNPC1RAB9A | |
| SCHEMBL6987496 | 0.77 | MTNR1A (0.46) | FFAR1ALDH1A1HPGDNPC1RAB9A | |
| SCHEMBL6535462 | 0.77 | FFAR1 (0.43) | FFAR1ALDH1A1HPGDNPC1RAB9A |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-4334287-A1 | NLRP3 INFLAMMASOME-INHIBITING COMPOUNDS AND THE USE THEREOF | Università Degli Studi Di Torino (IT) | 2024-03-13 | — | — | EP | disclosed |
| WO-2022234447-A1 | NLRP3 INFLAMMASOME-INHIBITING COMPOUNDS AND THE USE THEREOF | UNIVERSITA' DEGLI STUDI DI TORINO (IT) | 2022-11-10 | — | — | WO | disclosed |