Predicted protein targets (top 5)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | MAPK1 | P28482 | 1/20 | 0.40 |
| ▸ | TSHR | P16473 | 4/20 | 0.33 |
| ▸ | LMNA | P02545 | 2/20 | 0.33 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.33 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.30 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL3264980 | 0.88 | — | — | |
| Ammonia Solution, Strong SCHEMBL28033697 | 0.82 | TSHR (0.33) | TSHRALDH1A1TDP1 | |
| SCHEMBL11296882 | 0.78 | — | — | |
| SCHEMBL11552753 | 0.77 | MAPK1 (0.37) | MAPK1TSHR | |
| SCHEMBL1114762 | 0.76 | MMP8 (0.34) | — | |
| SCHEMBL3825740 | 0.74 | CYP4F2 (0.31) | ALDH1A1 | |
| SCHEMBL4605879 | 0.74 | MEN1 (0.40) | LMNA | |
| SCHEMBL5708413 | 0.72 | — | — | |
| SCHEMBL3837098 | 0.72 | — | — | |
| SCHEMBL30366434 | 0.72 | — | — |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-5155268-A | Antiarrhythmic N-aminoalkylene alkyl and aryl sulfonamides | THE UPJOHN COMPANY (US) | 1992-10-13 | — | — | US | disclosed |