SCHEMBL9624599

SCHEMBL9624599

C=CCOCC(C)(CO[Si](C)(C)C)CO[Si](C)(C)C

nearest known ligand 0.31

Predicted protein targets (top 4)

geneUniProtsupporting neighboursconfidence
ALDH1A1 P00352 1/20 0.31
MEN1 O00255 1/20 0.31
POLB P06746 1/20 0.31
KMT2A Q03164 1/20 0.31

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL826570 0.85 MEN1 (0.38) ALDH1A1MEN1POLBKMT2A
SCHEMBL9187830 0.78
SCHEMBL3308475 0.77 THRB (0.41) MEN1POLBKMT2A
SCHEMBL10345959 0.77 THRB (0.41) MEN1POLBKMT2A
SCHEMBL15096043 0.77 MEN1 (0.38) ALDH1A1MEN1POLBKMT2A
SCHEMBL20202300 0.77 MEN1 (0.33) ALDH1A1MEN1POLBKMT2A
SCHEMBL5550335 0.74
SCHEMBL9387822 0.74 MEN1 (0.39) ALDH1A1MEN1POLBKMT2A
SCHEMBL21028770 0.74 MEN1 (0.39) ALDH1A1MEN1POLBKMT2A
SCHEMBL272880 0.72 CA1 (0.33) ALDH1A1MEN1POLBKMT2A

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
EP-0277816-B1 A POLYSILOXANE CONTAINING HYDROXYL GROUPS AND A SILICONE-MODIFIED POLYURETHANE USING THE SAME Chisso Corporation (JP) 1992-01-29 EP disclosed
US-4839443-A WATER, OIL REPELLENCY; FRICTION, THROMBOSIS RESISTANCE CHISSO CORPORATION (JP) 1989-06-13 US disclosed
EP-0277816-A1 A polysiloxane containing hydroxyl groups and a silicone-modified polyurethane using the same Chisso Corporation (JP) 1988-08-10 EP disclosed