SCHEMBL10345959

SCHEMBL10345959

C=CCOCC(CC)(CO[Si](C)(C)C)CO[Si](C)(C)C

nearest known ligand 0.41

Predicted protein targets (top 4)

geneUniProtsupporting neighboursconfidence
THRB P10828 1/20 0.41
MEN1 O00255 1/20 0.32
POLB P06746 1/20 0.32
KMT2A Q03164 1/20 0.32

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL3308475 1.00 THRB (0.41) THRBMEN1POLBKMT2A
SCHEMBL160932 0.86 THRB (0.46) THRBMEN1POLBKMT2A
SCHEMBL13486283 0.82 THRB (0.46) THRBMEN1POLBKMT2A
SCHEMBL14253082 0.82 THRB (0.41) THRBMEN1POLBKMT2A
SCHEMBL9714530 0.79 THRB (0.32) THRB
SCHEMBL12250337 0.79 THRB (0.41) THRBMEN1POLBKMT2A
SCHEMBL20435059 0.79 THRB (0.41) THRBMEN1POLBKMT2A
SCHEMBL9624599 0.77 ALDH1A1 (0.31) MEN1POLBKMT2A
SCHEMBL12858519 0.77 THRB (0.43) THRBMEN1POLBKMT2A
SCHEMBL14706846 0.77 THRB (0.47) THRBMEN1POLBKMT2A

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
EP-0356963-A2 Novel siloxane compounds terminated with a diol at one end thereof Shin-Etsu Chemical Co., Ltd. (JP) 1990-03-07 EP disclosed