Predicted protein targets (top 5)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | NAAA | Q02083 | 1/20 | 0.35 |
| ▸ | RAB9A | P51151 | 1/20 | 0.34 |
| ▸ | CTSL | P07711 | 1/20 | 0.32 |
| ▸ | MAPT | P10636 | 1/20 | 0.32 |
| ▸ | HCN4 | Q9Y3Q4 | 1/20 | 0.32 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL9624509 | 0.99 | NAAA (0.37) | NAAARAB9A | |
| SCHEMBL9624809 | 0.97 | RAB9A (0.34) | NAAARAB9ACTSLMAPTHCN4 | |
| SCHEMBL9625096 | 0.95 | MAPT (0.36) | RAB9ACTSLMAPTHCN4 | |
| SCHEMBL9624963 | 0.86 | HDAC6 (0.34) | NAAAMAPTHCN4 | |
| SCHEMBL9625068 | 0.85 | HDAC6 (0.35) | NAAAMAPTHCN4 | |
| SCHEMBL9624538 | 0.83 | BCHE (0.37) | RAB9ACTSL | |
| SCHEMBL9624931 | 0.83 | HCN4 (0.46) | MAPTHCN4 | |
| SCHEMBL9623769 | 0.83 | SMN1; SMN2 (0.39) | RAB9A | |
| SCHEMBL9623887 | 0.83 | HDAC6 (0.34) | NAAAMAPTHCN4 | |
| SCHEMBL9624761 | 0.83 | HCN4 (0.45) | NAAAMAPTHCN4 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-5116986-A | HETEROAROMATIC AMINE DERIVATIVES | DR. KARL THOMAE GMBH (DE) | 1992-05-26 | — | — | US | disclosed |
| US-4912115-A | Cardiovascular disorders | DR. KARL THOMAE GMBH (DE) | 1990-03-27 | — | — | US | disclosed |