Predicted protein targets (top 3)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ESR1 | P03372 | 6/20 | 0.42 |
| ▸ | ESR2 | Q92731 | 6/20 | 0.42 |
| ▸ | GRIN2B | Q13224 | 1/20 | 0.31 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL1853872 | 0.77 | ADRA2A (0.35) | — | |
| SCHEMBL20741307 | 0.77 | ADRA2A (0.35) | — | |
| SCHEMBL20741308 | 0.77 | ADRA2A (0.35) | — | |
| SCHEMBL15332425 | 0.74 | ALDH1A1 (0.35) | — | |
| SCHEMBL2563540 | 0.74 | ALDH1A1 (0.35) | — | |
| SCHEMBL15022592 | 0.74 | ESR1 (0.55) | ESR1ESR2GRIN2B | |
| SCHEMBL15022591 | 0.74 | ESR1 (0.55) | ESR1ESR2GRIN2B | |
| SCHEMBL3722303 | 0.74 | ESR1 (0.55) | ESR1ESR2GRIN2B | |
| SCHEMBL2897054 | 0.70 | ESR1 (0.50) | ESR1ESR2GRIN2B | |
| SCHEMBL28470383 | 0.69 | MEN1 (0.43) | ESR1ESR2 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 11 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0241428-B1 | USE OF 2-AMINOALKYL-5-PYRIDINOL COMPOUNDS AS NOOTROPICS AND ANTIDEPRESSANTS | CIBA-GEIGY AG (CH) | 1992-03-18 | — | — | EP | claimed |
| US-4746670-A | Use of 2-aminoalkyl-5-pyridinols as nootropic agents and antidepressants | CIBA-GEIGY CORPORATION (US) | 1988-05-24 | — | — | US | claimed |
| EP-0019739-B1 | 2-AMINOALKYL-5-PYRIDINOLES, PROCESS FOR THEIR PREPARATION AND PHARMACEUTICAL PREPARATIONS CONTAINING THEM | CIBA-GEIGY AG (CH) | 1984-07-18 | — | — | EP | claimed |
| US-4260619-A | ANTIISCHEMIC | CIBA-GEIGY CORPORATION (US) | 1981-04-07 | — | — | US | claimed |
| EP-0241428-B1 | USE OF 2-AMINOALKYL-5-PYRIDINOL COMPOUNDS AS NOOTROPICS AND ANTIDEPRESSANTS | CIBA-GEIGY AG (CH) | 1992-03-18 | — | — | EP | disclosed |
| US-4746670-A | Use of 2-aminoalkyl-5-pyridinols as nootropic agents and antidepressants | CIBA-GEIGY CORPORATION (US) | 1988-05-24 | — | — | US | disclosed |
| US-4746670-A | Use of 2-aminoalkyl-5-pyridinols as nootropic agents and antidepressants | CIBA-GEIGY CORPORATION (US) | 1988-05-24 | — | — | US | disclosed |
| EP-0241428-A2 | Use of 2-aminoalkyl-5-pyridinol compounds as nootropics and antidepressants | CIBA-GEIGY AG (CH) | 1987-10-14 | — | — | EP | disclosed |
| US-4260619-A | ANTIISCHEMIC | CIBA-GEIGY CORPORATION (US) | 1981-04-07 | — | — | US | disclosed |
| US-4260619-A | ANTIISCHEMIC | CIBA-GEIGY CORPORATION (US) | 1981-04-07 | — | — | US | disclosed |
| US-4260619-A | ANTIISCHEMIC | CIBA-GEIGY CORPORATION (US) | 1981-04-07 | — | — | US | disclosed |