Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | THRA | P10827 | 1/20 | 0.47 |
| ▸ | THRB | P10828 | 1/20 | 0.47 |
| ▸ | HTR7 | P34969 | 1/20 | 0.41 |
| ▸ | PLA2G2A | P14555 | 1/20 | 0.41 |
| ▸ | HSD17B3 | P37058 | 6/20 | 0.41 |
| ▸ | MGLL | Q99685 | 3/20 | 0.40 |
| ▸ | PTPN11 | Q06124 | 1/20 | 0.40 |
| ▸ | HDAC3 | O15379 | 1/20 | 0.38 |
| ▸ | HDAC4 | P56524 | 1/20 | 0.38 |
| ▸ | HDAC1 | Q13547 | 1/20 | 0.38 |
| ▸ | HDAC7 | Q8WUI4 | 1/20 | 0.38 |
| ▸ | HDAC2 | Q92769 | 1/20 | 0.38 |
| ▸ | HDAC10 | Q969S8 | 1/20 | 0.38 |
| ▸ | HDAC11 | Q96DB2 | 1/20 | 0.38 |
| ▸ | HDAC8 | Q9BY41 | 1/20 | 0.38 |
| ▸ | HDAC6 | Q9UBN7 | 1/20 | 0.38 |
| ▸ | HDAC9 | Q9UKV0 | 1/20 | 0.38 |
| ▸ | HDAC5 | Q9UQL6 | 1/20 | 0.38 |
| ▸ | STS | P08842 | 3/20 | 0.38 |
| ▸ | LMNA | P02545 | 2/20 | 0.38 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL9625970 | 0.99 | THRA (0.47) | THRATHRBHTR7PLA2G2AHSD17B3 | |
| SCHEMBL9625309 | 0.96 | THRA (0.47) | THRATHRBHTR7PLA2G2AHSD17B3 | |
| SCHEMBL9624618 | 0.92 | THRA (0.43) | THRATHRBHTR7PLA2G2AHSD17B3 | |
| SCHEMBL9624389 | 0.88 | MAPT (0.48) | THRATHRBPLA2G2AHSD17B3PTPN11 | |
| SCHEMBL9625680 | 0.87 | RARB (0.53) | MGLL | |
| SCHEMBL9624652 | 0.87 | MAPT (0.49) | THRATHRBPLA2G2AHSD17B3PTPN11 | |
| SCHEMBL9625651 | 0.86 | RARB (0.51) | THRATHRBMGLLPTPN11 | |
| SCHEMBL9625917 | 0.86 | RARB (0.51) | MGLL | |
| SCHEMBL9624585 | 0.85 | THRA (0.45) | THRATHRBMGLLPTPN11 | |
| SCHEMBL9625619 | 0.85 | THRA (0.45) | THRATHRBMGLLPTPN11 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0255219-B1 | OMEGA-SUBSTITUTED, OPTICALLY ACTIVE 2-ALKANOL ESTER DERIVATIVES | Chisso Corporation (JP) | 1992-03-11 | — | — | EP | disclosed |
| US-5047172-A | W-substituted, optically active alkanol ester derivatives | CHISSO CORPORATION (JP) | 1991-09-10 | — | — | US | disclosed |