Predicted protein targets (top 16)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | RARB | P10826 | 10/20 | 0.51 |
| ▸ | RARA | P10276 | 3/20 | 0.51 |
| ▸ | RARG | P13631 | 1/20 | 0.51 |
| ▸ | S1PR1 | P21453 | 1/20 | 0.42 |
| ▸ | ALOX15 | P16050 | 1/20 | 0.41 |
| ▸ | MGLL | Q99685 | 5/20 | 0.40 |
| ▸ | MEN1 | O00255 | 1/20 | 0.40 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.40 |
| ▸ | MAPT | P10636 | 1/20 | 0.40 |
| ▸ | MTOR | P42345 | 1/20 | 0.40 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.40 |
| ▸ | PTPN1 | P18031 | 1/20 | 0.38 |
| ▸ | PTPN6 | P29350 | 1/20 | 0.38 |
| ▸ | PTPN11 | Q06124 | 1/20 | 0.38 |
| ▸ | THRA | P10827 | 1/20 | 0.37 |
| ▸ | THRB | P10828 | 1/20 | 0.37 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL9625917 | 0.98 | RARB (0.51) | RARBRARARARGS1PR1ALOX15 | |
| SCHEMBL9625680 | 0.97 | RARB (0.53) | RARBRARARARGS1PR1ALOX15 | |
| SCHEMBL9624794 | 0.93 | RARB (0.52) | RARBRARARARGS1PR1ALOX15 | |
| SCHEMBL9624704 | 0.88 | RAB9A (0.47) | RARBRARARARGALOX15ALDH1A1 | |
| SCHEMBL9624108 | 0.87 | RARB (0.47) | RARBRARARARGS1PR1ALOX15 | |
| SCHEMBL9625251 | 0.86 | THRA (0.47) | MGLLPTPN11THRATHRB | |
| SCHEMBL9624585 | 0.84 | THRA (0.45) | RARBRARAS1PR1MGLLPTPN1 | |
| SCHEMBL9625970 | 0.84 | THRA (0.47) | MGLLPTPN11THRATHRB | |
| SCHEMBL9625207 | 0.83 | S1PR1 (0.47) | RARBRARAS1PR1MGLLMEN1 | |
| SCHEMBL9625619 | 0.82 | THRA (0.45) | RARBRARAS1PR1MGLLPTPN1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0255219-B1 | OMEGA-SUBSTITUTED, OPTICALLY ACTIVE 2-ALKANOL ESTER DERIVATIVES | Chisso Corporation (JP) | 1992-03-11 | — | — | EP | disclosed |
| US-5047172-A | W-substituted, optically active alkanol ester derivatives | CHISSO CORPORATION (JP) | 1991-09-10 | — | — | US | disclosed |