Predicted protein targets (top 1)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | SHBG | P04278 | 1/20 | 0.31 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL5723992 | 1.00 | SHBG (0.31) | SHBG | |
| SCHEMBL486973 | 0.85 | CYP2D6 (0.36) | — | |
| SCHEMBL486945 | 0.85 | CYP2D6 (0.36) | — | |
| SCHEMBL958474 | 0.84 | — | — | |
| SCHEMBL487249 | 0.81 | CYP2D6 (0.33) | — | |
| SCHEMBL496913 | 0.78 | — | — | |
| SCHEMBL7739593 | 0.74 | CYP2D6 (0.31) | — | |
| SCHEMBL7741445 | 0.74 | CYP2D6 (0.31) | — | |
| SCHEMBL7737776 | 0.74 | CYP2D6 (0.31) | — | |
| SCHEMBL258217 | 0.74 | CYP2D6 (0.31) | — |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-5155268-A | Antiarrhythmic N-aminoalkylene alkyl and aryl sulfonamides | THE UPJOHN COMPANY (US) | 1992-10-13 | — | — | US | disclosed |
| EP-0164865-B1 | N-(AMINOALKYLPHENYL)SULFONAMIDES THEIR PREPARATION AND THERAPEUTIC USE | THE UPJOHN COMPANY (US) | 1988-12-21 | — | — | EP | disclosed |
| EP-0164865-A1 | N-(Aminoalkylphenyl)sulfonamides their preparation and therapeutic use | THE UPJOHN COMPANY (US) | 1985-12-18 | — | — | EP | disclosed |