SCHEMBL9625958

SCHEMBL9625958

CCCC(O)OC(C)(C)C

nearest known ligand 0.33

Predicted protein targets (top 3)

geneUniProtsupporting neighboursconfidence
TSHR P16473 3/20 0.33
MAPK1 P28482 1/20 0.33
LMNA P02545 1/20 0.31

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL15975336 1.00 TSHR (0.33) TSHRMAPK1LMNA
SCHEMBL12163490 0.85 CA2 (0.38) MAPK1
SCHEMBL10932492 0.82 TSHR (0.32) TSHRLMNA
SCHEMBL28470882 0.81 SMPD1 (0.42) LMNA
SCHEMBL14754924 0.79 THRB (0.39) MAPK1
SCHEMBL28860849 0.78 MAPK1 (0.30) MAPK1
SCHEMBL12918353 0.78 TSHR (0.32) TSHRMAPK1
SCHEMBL754933 0.78
SCHEMBL14401790 0.77 MAPK1 (0.32) MAPK1
SCHEMBL9308935 0.77 TSHR (0.32) TSHRLMNA

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 9 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
EP-0024532-B2 TERT. BUTOXYBUTANALES AND BUTANOLES AND BIS-TERT. BUTOXY-PENTANALES AND PENTANOLES, THEIR PRODUCTION AND THEIR USE AS PERFUMES BASF Aktiengesellschaft (DE) 1984-08-15 EP claimed
EP-0024532-B1 TERT. BUTOXYBUTANALES AND BUTANOLES AND BIS-TERT. BUTOXY-PENTANALES AND PENTANOLES, THEIR PRODUCTION AND THEIR USE AS PERFUMES BASF Aktiengesellschaft (DE) 1982-06-23 EP claimed
CN-103917526-B Pyrimidine carboxamide derivatives 南京优迪生物医药有限公司 2016-08-24 CN disclosed
EP-0300018-B1 HYDROGENATION PROCESS DAVY McKEE (LONDON) LIMITED (GB) 1992-06-17 EP disclosed
EP-0319208-B1 PROCESS FOR HYDROGENATING DAVY McKEE (LONDON) LIMITED (GB) 1992-04-15 EP disclosed
EP-0319208-A1 Process for hydrogenating DAVY McKEE (LONDON) LIMITED (GB) 1989-06-07 EP disclosed
US-4418216-A Bis-tert.-butoxypentanals and bis-tert.-butoxypentanols BASF AKTIENGESELLSCHAFT (DE) 1983-11-29 US disclosed
US-4409402-A FRAGRANCES; CHEMICAL INTERMEDIATES BASF AKTIENGESELLSCHAFT (DE) 1983-10-11 US disclosed
US-4409402-A FRAGRANCES; CHEMICAL INTERMEDIATES BASF AKTIENGESELLSCHAFT (DE) 1983-10-11 US disclosed