Predicted protein targets (top 10)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | RARB | P10826 | 8/20 | 0.51 |
| ▸ | RARG | P13631 | 8/20 | 0.51 |
| ▸ | RARA | P10276 | 6/20 | 0.51 |
| ▸ | RXRA | P19793 | 9/20 | 0.49 |
| ▸ | RXRB | P28702 | 8/20 | 0.49 |
| ▸ | CYP3A4 | P08684 | 3/20 | 0.45 |
| ▸ | CYP26A1 | O43174 | 2/20 | 0.45 |
| ▸ | CYP26B1 | Q9NR63 | 1/20 | 0.45 |
| ▸ | RXRG | P48443 | 5/20 | 0.41 |
| ▸ | PPARG | P37231 | 3/20 | 0.38 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL9626066 | 0.81 | RXRA (0.46) | RARBRARGRARARXRARXRB | |
| SCHEMBL3175854 | 0.79 | RXRA (0.57) | RARBRARGRARARXRARXRB | |
| SCHEMBL6147437 | 0.77 | RARB (0.57) | RARBRARGRARARXRARXRB | |
| SCHEMBL9626370 | 0.77 | RARA (0.40) | RARBRARGRARARXRARXRB | |
| SCHEMBL9551729 | 0.77 | RARB (0.54) | RARBRARGRARARXRARXRB | |
| SCHEMBL5847922 | 0.76 | RARA (0.39) | RARBRARGRARARXRARXRB | |
| SCHEMBL9626012 | 0.76 | RARA (0.39) | RARBRARGRARARXRARXRB | |
| SCHEMBL11240964 | 0.76 | RXRA (0.54) | RARBRARGRARARXRARXRB | |
| SCHEMBL3541162 | 0.76 | RXRA (0.58) | RARBRARGRARARXRARXRB | |
| SCHEMBL9266797 | 0.74 | CYP3A4 (0.44) | RARBRARGRARARXRARXRB |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0339521-B1 | PROCESS FOR MANUFACTURING TETRALIN DERIVATIVES, AND TETRALIN DERIVATIVES | BASF Aktiengesellschaft (DE) | 1992-03-18 | — | — | EP | disclosed |
| US-4950369-A | Preparation of tetralin derivatives, and novel tetralin derivatives | BASF AKTIENGESELLSCHAFT (DE) | 1990-08-21 | — | — | US | disclosed |
| EP-0339521-A1 | Process for manufacturing tetralin derivatives, and tetralin derivatives | BASF Aktiengesellschaft (DE) | 1989-11-02 | — | — | EP | disclosed |