Predicted protein targets (top 8)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | FFAR1 | O14842 | 15/20 | 0.79 |
| ▸ | FFAR4 | Q5NUL3 | 6/20 | 0.79 |
| ▸ | MAOB | P27338 | 2/20 | 0.56 |
| ▸ | AKR1B1 | P15121 | 1/20 | 0.53 |
| ▸ | CYP19A1 | P11511 | 1/20 | 0.50 |
| ▸ | CYP11B1 | P15538 | 1/20 | 0.50 |
| ▸ | CYP11B2 | P19099 | 1/20 | 0.50 |
| ▸ | KCNH2 | Q12809 | 1/20 | 0.50 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL6364918 | 0.85 | FFAR1 (0.55) | FFAR1FFAR4KCNH2 | |
| SCHEMBL9626622 | 0.82 | MAOB (0.65) | FFAR1FFAR4MAOBAKR1B1 | |
| SCHEMBL9626424 | 0.82 | MAOB (0.69) | FFAR1FFAR4MAOBAKR1B1 | |
| SCHEMBL9626407 | 0.82 | MAOB (0.69) | FFAR1FFAR4MAOBAKR1B1 | |
| SCHEMBL5033197 | 0.81 | FFAR1 (0.77) | FFAR1FFAR4MAOBAKR1B1 | |
| SCHEMBL9627314 | 0.80 | FFAR1 (0.68) | FFAR1FFAR4MAOBCYP19A1CYP11B1 | |
| SCHEMBL14163905 | 0.79 | FFAR1 (0.63) | FFAR1FFAR4MAOBCYP19A1CYP11B1 | |
| SCHEMBL7849454 | 0.78 | FFAR1 (0.62) | FFAR1FFAR4MAOBCYP19A1CYP11B1 | |
| SCHEMBL13232461 | 0.78 | GRM5 (0.62) | FFAR1FFAR4MAOBCYP19A1CYP11B1 | |
| SCHEMBL8549374 | 0.78 | FFAR1 (0.60) | FFAR1FFAR4MAOB |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0477184-A1 | INHIBITORS OF MONO-AMINE OXIDASE, PROCESS FOR THEIR PREPARATION, AND THEIR USE IN THERAPEUTICS. | FOURNIER INDUSTRIE ET SANTE (FR) | 1992-04-01 | — | — | EP | disclosed |
| WO-1990011997-A2 | INHIBITORS OF MONO-AMINE OXIDASE, PROCESS FOR THEIR PREPARATION, AND THEIR USE IN THERAPEUTICS. | FOURNIER INNOVATION ET SYNERGIE (FR) | 1990-10-18 | — | — | WO | disclosed |