Predicted protein targets (top 11)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | MAOB | P27338 | 8/20 | 0.69 |
| ▸ | MAOA | P21397 | 3/20 | 0.69 |
| ▸ | ALOX5 | P09917 | 1/20 | 0.63 |
| ▸ | RXRA | P19793 | 1/20 | 0.63 |
| ▸ | RXRB | P28702 | 1/20 | 0.63 |
| ▸ | RXRG | P48443 | 1/20 | 0.63 |
| ▸ | FFAR1 | O14842 | 4/20 | 0.56 |
| ▸ | FFAR4 | Q5NUL3 | 3/20 | 0.56 |
| ▸ | AKR1B1 | P15121 | 1/20 | 0.55 |
| ▸ | S1PR1 | P21453 | 1/20 | 0.55 |
| ▸ | S1PR5 | Q9H228 | 1/20 | 0.55 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL9626404 | 0.88 | FFAR1 (0.56) | MAOBMAOAALOX5RXRARXRB | |
| SCHEMBL9627231 | 0.85 | MAOB (0.74) | MAOBMAOAALOX5RXRARXRB | |
| SCHEMBL9627289 | 0.84 | MAOB (0.68) | MAOBMAOAFFAR1FFAR4 | |
| SCHEMBL8935287 | 0.84 | MAOB (0.64) | MAOBMAOAALOX5RXRARXRB | |
| SCHEMBL9626407 | 0.84 | MAOB (0.69) | MAOBMAOAFFAR1FFAR4AKR1B1 | |
| SCHEMBL9626622 | 0.84 | MAOB (0.65) | MAOBMAOAFFAR1FFAR4AKR1B1 | |
| SCHEMBL5038560 | 0.84 | MAOB (0.58) | MAOBMAOAALOX5RXRARXRB | |
| SCHEMBL5033197 | 0.83 | FFAR1 (0.77) | MAOBALOX5FFAR1FFAR4AKR1B1 | |
| SCHEMBL1848 | 0.82 | ALDH1A1 (0.60) | MAOBMAOAFFAR1FFAR4 | |
| SCHEMBL9626352 | 0.82 | FFAR1 (0.79) | MAOBFFAR1FFAR4AKR1B1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0477184-A1 | INHIBITORS OF MONO-AMINE OXIDASE, PROCESS FOR THEIR PREPARATION, AND THEIR USE IN THERAPEUTICS. | FOURNIER INDUSTRIE ET SANTE (FR) | 1992-04-01 | — | — | EP | disclosed |
| WO-1990011997-A2 | INHIBITORS OF MONO-AMINE OXIDASE, PROCESS FOR THEIR PREPARATION, AND THEIR USE IN THERAPEUTICS. | FOURNIER INNOVATION ET SYNERGIE (FR) | 1990-10-18 | — | — | WO | disclosed |