SCHEMBL9626463

SCHEMBL9626463

COCCCc1ccc(OCc2cccc(Cl)c2)cc1

nearest known ligand 0.64

Predicted protein targets (top 8)

geneUniProtsupporting neighboursconfidence
MAOB P27338 6/20 0.64
MAOA P21397 2/20 0.56
ENPP2 Q13822 1/20 0.55
ALOX5 P09917 1/20 0.54
RXRA P19793 1/20 0.53
RXRB P28702 1/20 0.53
RXRG P48443 1/20 0.53
DHFR P00374 1/20 0.49

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL9626584 0.83 LTA4H (0.68) MAOBMAOAALOX5RXRARXRB
SCHEMBL11473762 0.82 LTA4H (0.66)
SCHEMBL9627104 0.82 MAOB (0.66) MAOBMAOAALOX5RXRARXRB
SCHEMBL15061331 0.82 MAOB (0.66) MAOBMAOAALOX5RXRARXRB
SCHEMBL9628272 0.80 MAOB (0.60) MAOBMAOAALOX5RXRARXRB
SCHEMBL9628508 0.80 MAOB (0.71) MAOBMAOAALOX5RXRARXRB
SCHEMBL4417319 0.79 MAOB (0.73) MAOBMAOAALOX5RXRARXRB
Hydrochloric Acid SCHEMBL7429625 0.78 MAOB (1.00) MAOBMAOARXRARXRBRXRG
SCHEMBL9626408 0.78 MAOB (0.57) MAOBMAOAALOX5RXRARXRB
SCHEMBL10169470 0.77 MAOB (0.71) MAOBMAOAALOX5RXRARXRB

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
EP-0477184-A1 INHIBITORS OF MONO-AMINE OXIDASE, PROCESS FOR THEIR PREPARATION, AND THEIR USE IN THERAPEUTICS. FOURNIER INDUSTRIE ET SANTE (FR) 1992-04-01 EP disclosed
WO-1990011997-A2 INHIBITORS OF MONO-AMINE OXIDASE, PROCESS FOR THEIR PREPARATION, AND THEIR USE IN THERAPEUTICS. FOURNIER INNOVATION ET SYNERGIE (FR) 1990-10-18 WO disclosed