Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | SLC2A1 | P11166 | 1/20 | 0.42 |
| ▸ | ADRB2 | P07550 | 3/20 | 0.38 |
| ▸ | ADRB1 | P08588 | 3/20 | 0.38 |
| ▸ | HTR1A | P08908 | 2/20 | 0.38 |
| ▸ | OPRK1 | P41145 | 1/20 | 0.38 |
| ▸ | MAPT | P10636 | 2/20 | 0.38 |
| ▸ | LMNA | P02545 | 1/20 | 0.38 |
| ▸ | NPY1R | P25929 | 1/20 | 0.38 |
| ▸ | NPY2R | P49146 | 1/20 | 0.38 |
| ▸ | CYP2D6 | P10635 | 1/20 | 0.37 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.36 |
| ▸ | ADRB3 | P13945 | 2/20 | 0.35 |
| ▸ | PDE3B | Q13370 | 2/20 | 0.35 |
| ▸ | KCNH2 | Q12809 | 1/20 | 0.35 |
| ▸ | PDE4A | P27815 | 1/20 | 0.35 |
| ▸ | PDE4B | Q07343 | 1/20 | 0.35 |
| ▸ | PDE4C | Q08493 | 1/20 | 0.35 |
| ▸ | PDE4D | Q08499 | 1/20 | 0.35 |
| ▸ | PDE3A | Q14432 | 1/20 | 0.35 |
| ▸ | TSHR | P16473 | 1/20 | 0.33 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL9626518 | 1.00 | SLC2A1 (0.42) | SLC2A1ADRB2ADRB1HTR1AOPRK1 | |
| SCHEMBL9462359 | 0.92 | SLC2A1 (0.46) | SLC2A1ADRB2ADRB1HTR1AOPRK1 | |
| SCHEMBL9462848 | 0.92 | SLC2A1 (0.46) | SLC2A1ADRB2ADRB1HTR1AOPRK1 | |
| SCHEMBL9462328 | 0.91 | ADRB2 (0.39) | SLC2A1ADRB2ADRB1HTR1AOPRK1 | |
| SCHEMBL9462614 | 0.91 | SLC2A1 (0.43) | SLC2A1ADRB2ADRB1HTR1AOPRK1 | |
| SCHEMBL9462609 | 0.91 | SLC2A1 (0.43) | SLC2A1ADRB2ADRB1HTR1AOPRK1 | |
| SCHEMBL9462487 | 0.89 | SLC2A1 (0.41) | SLC2A1ADRB2ADRB1HTR1AOPRK1 | |
| SCHEMBL9462305 | 0.89 | SLC2A1 (0.41) | SLC2A1ADRB2ADRB1HTR1AOPRK1 | |
| SCHEMBL9656783 | 0.87 | PDE3B (0.44) | SLC2A1MAPTLMNACYP2D6PDE3B | |
| SCHEMBL9463196 | 0.85 | SLC2A1 (0.41) | SLC2A1ADRB2ADRB1HTR1AOPRK1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-5130314-A | Hypotensive agents | TEIKOKU HORMONE MFG. CO., LTD. (JP) | 1992-07-14 | — | — | US | disclosed |
| US-5082844-A | Hypotensive | TEIKOKU HORMONE MFG. CO., LTD. (JP) | 1992-01-21 | — | — | US | disclosed |