Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | SLC2A1 | P11166 | 1/20 | 0.41 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.40 |
| ▸ | ADRB2 | P07550 | 3/20 | 0.39 |
| ▸ | ADRB1 | P08588 | 3/20 | 0.39 |
| ▸ | HTR1A | P08908 | 2/20 | 0.39 |
| ▸ | OPRK1 | P41145 | 1/20 | 0.39 |
| ▸ | CASR | P41180 | 1/20 | 0.37 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.36 |
| ▸ | MAPT | P10636 | 2/20 | 0.36 |
| ▸ | NPSR1 | Q6W5P4 | 2/20 | 0.36 |
| ▸ | MEN1 | O00255 | 1/20 | 0.36 |
| ▸ | HTT | P42858 | 1/20 | 0.36 |
| ▸ | LMNA | P02545 | 1/20 | 0.36 |
| ▸ | NPY1R | P25929 | 1/20 | 0.36 |
| ▸ | NPY2R | P49146 | 1/20 | 0.36 |
| ▸ | PDE3B | Q13370 | 2/20 | 0.35 |
| ▸ | KCNH2 | Q12809 | 1/20 | 0.35 |
| ▸ | PDE4A | P27815 | 1/20 | 0.35 |
| ▸ | PDE4B | Q07343 | 1/20 | 0.35 |
| ▸ | PDE4C | Q08493 | 1/20 | 0.35 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL9463189 | 1.00 | SLC2A1 (0.41) | SLC2A1L3MBTL1ADRB2ADRB1HTR1A | |
| SCHEMBL9462359 | 0.93 | SLC2A1 (0.46) | SLC2A1ADRB2ADRB1HTR1AOPRK1 | |
| SCHEMBL9462848 | 0.93 | SLC2A1 (0.46) | SLC2A1ADRB2ADRB1HTR1AOPRK1 | |
| SCHEMBL9462394 | 0.92 | L3MBTL1 (0.41) | SLC2A1L3MBTL1ADRB2ADRB1HTR1A | |
| SCHEMBL9462681 | 0.90 | SLC2A1 (0.38) | SLC2A1ADRB2ADRB1HTR1AOPRK1 | |
| SCHEMBL9462679 | 0.90 | SLC2A1 (0.38) | SLC2A1ADRB2ADRB1HTR1AOPRK1 | |
| SCHEMBL9626468 | 0.89 | CASR (0.38) | SLC2A1ADRB2ADRB1HTR1AOPRK1 | |
| SCHEMBL9462437 | 0.89 | CASR (0.38) | SLC2A1ADRB2ADRB1HTR1AOPRK1 | |
| SCHEMBL9462643 | 0.89 | ADRB2 (0.41) | SLC2A1L3MBTL1ADRB2ADRB1HTR1A | |
| SCHEMBL9462609 | 0.87 | SLC2A1 (0.43) | SLC2A1ADRB2ADRB1HTR1AOPRK1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 4 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-5221674-A | Hypotensive agents having beta-blocking and vasodilation activity | TEIKOKU HORMONE MFG. CO., LTD. (JP) | 1993-06-22 | — | — | US | disclosed |
| US-5130314-A | Hypotensive agents | TEIKOKU HORMONE MFG. CO., LTD. (JP) | 1992-07-14 | — | — | US | disclosed |
| US-5082844-A | Hypotensive | TEIKOKU HORMONE MFG. CO., LTD. (JP) | 1992-01-21 | — | — | US | disclosed |
| EP-0404050-A1 | Pyridazinone derivatives | TEIKOKU HORMONE MFG. CO., LTD. (JP) | 1990-12-27 | — | — | EP | disclosed |