Predicted protein targets (top 9)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | NFKB1 | P19838 | 1/20 | 0.49 |
| ▸ | NFKB2 | Q00653 | 1/20 | 0.49 |
| ▸ | RELA | Q04206 | 1/20 | 0.49 |
| ▸ | LTB4R | Q15722 | 2/20 | 0.46 |
| ▸ | FPR2 | P25090 | 6/20 | 0.45 |
| ▸ | PPARG | P37231 | 4/20 | 0.45 |
| ▸ | PPARA | Q07869 | 2/20 | 0.45 |
| ▸ | FAAH | O00519 | 1/20 | 0.39 |
| ▸ | PTGER2 | P43116 | 1/20 | 0.38 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL8772243 | 0.93 | LTB4R (0.52) | NFKB1NFKB2RELALTB4RFPR2 | |
| SCHEMBL8772138 | 0.93 | LTB4R (0.52) | NFKB1NFKB2RELALTB4RFPR2 | |
| SCHEMBL8772239 | 0.93 | LTB4R (0.52) | NFKB1NFKB2RELALTB4RFPR2 | |
| SCHEMBL8849692 | 0.83 | LTB4R (0.49) | NFKB1NFKB2RELALTB4RFPR2 | |
| SCHEMBL8849684 | 0.83 | LTB4R (0.49) | NFKB1NFKB2RELALTB4RFPR2 | |
| SCHEMBL8890568 | 0.81 | LTB4R (0.57) | NFKB1NFKB2RELALTB4RFPR2 | |
| SCHEMBL8772147 | 0.81 | LTB4R (0.57) | NFKB1NFKB2RELALTB4RFPR2 | |
| SCHEMBL8890563 | 0.81 | LTB4R (0.57) | NFKB1NFKB2RELALTB4RFPR2 | |
| SCHEMBL9512660 | 0.78 | PPARG (0.57) | NFKB1NFKB2RELAFPR2PPARG | |
| SCHEMBL8772227 | 0.77 | LTB4R (0.55) | NFKB1LTB4R |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0477311-A1 | NEW LEUCOTRIENE B 4? DERIVATIVES, METHODS OF PREPARING THEM AND THEIR USE AS DRUGS | SCHERING AKTIENGESELLSCHAFT (DE) | 1992-04-01 | — | — | EP | disclosed |
| WO-1991014676-A1 | NEW LEUCOTRIENE B4 DERIVATIVES, METHODS OF PREPARING THEM AND THEIR USE AS DRUGS | SCHERING AKTIENGESELLSCHAFT BERLIN UND BERGKAMEN (DE) | 1991-10-03 | — | — | WO | disclosed |