Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | LTB4R | Q15722 | 3/20 | 0.49 |
| ▸ | PPARG | P37231 | 5/20 | 0.48 |
| ▸ | PPARA | Q07869 | 3/20 | 0.48 |
| ▸ | NFKB1 | P19838 | 2/20 | 0.48 |
| ▸ | NFKB2 | Q00653 | 1/20 | 0.48 |
| ▸ | RELA | Q04206 | 1/20 | 0.48 |
| ▸ | PTGER4 | P35408 | 2/20 | 0.44 |
| ▸ | PTGER3 | P43115 | 2/20 | 0.44 |
| ▸ | PTGER2 | P43116 | 1/20 | 0.44 |
| ▸ | FPR2 | P25090 | 4/20 | 0.43 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.42 |
| ▸ | MTOR | P42345 | 1/20 | 0.42 |
| ▸ | PMP22 | Q01453 | 1/20 | 0.42 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.42 |
| ▸ | CYP3A4 | P08684 | 1/20 | 0.42 |
| ▸ | CYP2C9 | P11712 | 1/20 | 0.42 |
| ▸ | ALOX15 | P16050 | 1/20 | 0.42 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.42 |
| ▸ | PLIN1 | O60240 | 1/20 | 0.42 |
| ▸ | GAA | P10253 | 1/20 | 0.42 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL8849684 | 1.00 | LTB4R (0.49) | LTB4RPPARGPPARANFKB1NFKB2 | |
| SCHEMBL8849953 | 0.88 | LTB4R (0.62) | LTB4RPPARGPPARANFKB1NFKB2 | |
| SCHEMBL8849939 | 0.88 | LTB4R (0.62) | LTB4RPPARGPPARANFKB1NFKB2 | |
| SCHEMBL8772138 | 0.86 | LTB4R (0.52) | LTB4RPPARGPPARANFKB1NFKB2 | |
| SCHEMBL8772243 | 0.86 | LTB4R (0.52) | LTB4RPPARGPPARANFKB1NFKB2 | |
| SCHEMBL8772239 | 0.86 | LTB4R (0.52) | LTB4RPPARGPPARANFKB1NFKB2 | |
| SCHEMBL9626537 | 0.83 | NFKB1 (0.49) | LTB4RPPARGPPARANFKB1NFKB2 | |
| SCHEMBL8870460 | 0.82 | LTB4R (0.45) | LTB4RPPARGPPARANFKB1NFKB2 | |
| SCHEMBL8870668 | 0.79 | LTB4R (0.50) | LTB4RPPARGPPARANFKB1NFKB2 | |
| SCHEMBL8870701 | 0.79 | LTB4R (0.50) | LTB4RPPARGPPARANFKB1NFKB2 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0650953-B1 | Cyclised analogs of metabolites of fatty acids, process for their preparation and pharmaceutical compositions containing them | ADIR (FR) | 1997-06-04 | — | — | EP | disclosed |
| US-5599975-A | ANTICOAGULANTS | ADIR ET COMPAGNIE (FR) | 1997-02-04 | — | — | US | disclosed |
| EP-0650953-A1 | Cyclised analogs of metabolites of fatty acids, process for their preparation and pharmaceutical compositions containing them | ADIR ET COMPAGNIE (FR) | 1995-05-03 | — | — | EP | disclosed |