Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | KMT2A | Q03164 | 4/20 | 0.39 |
| ▸ | RAB9A | P51151 | 3/20 | 0.38 |
| ▸ | POLB | P06746 | 2/20 | 0.38 |
| ▸ | HTR7 | P34969 | 1/20 | 0.38 |
| ▸ | NPC1 | O15118 | 1/20 | 0.37 |
| ▸ | MEN1 | O00255 | 2/20 | 0.36 |
| ▸ | SLC6A3 | Q01959 | 2/20 | 0.35 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.35 |
| ▸ | PSIP1 | O75475 | 1/20 | 0.34 |
| ▸ | HSD11B1 | P28845 | 1/20 | 0.34 |
| ▸ | MMP1 | P03956 | 1/20 | 0.34 |
| ▸ | MMP13 | P45452 | 1/20 | 0.34 |
| ▸ | MMP2 | P08253 | 1/20 | 0.34 |
| ▸ | MMP3 | P08254 | 1/20 | 0.34 |
| ▸ | MMP9 | P14780 | 1/20 | 0.34 |
| ▸ | MMP14 | P50281 | 1/20 | 0.34 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.34 |
| ▸ | CA12 | O43570 | 1/20 | 0.33 |
| ▸ | CA1 | P00915 | 1/20 | 0.33 |
| ▸ | CA2 | P00918 | 1/20 | 0.33 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL7584043 | 0.81 | ALDH1A1 (0.39) | KMT2ARAB9APOLBHTR7NPC1 | |
| SCHEMBL6097183 | 0.78 | ALDH1A1 (0.38) | KMT2AMEN1SLC6A3ALDH1A1MMP1 | |
| SCHEMBL10911815 | 0.76 | KMT2A (0.41) | KMT2ARAB9ANPC1MEN1SLC6A3 | |
| SCHEMBL7050550 | 0.76 | SIGMAR1 (0.39) | KMT2AMEN1SLC6A3CA12CA1 | |
| SCHEMBL6097178 | 0.76 | KMT2A (0.51) | KMT2ARAB9APOLBHTR7NPC1 | |
| SCHEMBL9626734 | 0.75 | HPGD (0.39) | KMT2AMEN1SLC6A3ALDH1A1MAPT | |
| SCHEMBL9180023 | 0.75 | SLC6A3 (0.34) | KMT2ARAB9APOLBMEN1SLC6A3 | |
| SCHEMBL8505555 | 0.75 | SLC6A3 (0.34) | KMT2ARAB9APOLBMEN1SLC6A3 | |
| SCHEMBL27147707 | 0.74 | FKBP1A (0.37) | MMP1MMP2MMP3CA12CA1 | |
| SCHEMBL27131627 | 0.74 | FKBP1A (0.37) | MMP1MMP2MMP3CA12CA1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-5081152-A | AZULENE DERIVATIVES AS THROMBOXANE A2 AND PROSTAGLANDIN ENDOPEROXIDE RECEPTOR ANTAGONIST | KOTOBUKI SEIYAKU CO., LTD. (JP) | 1992-01-14 | — | — | US | disclosed |