Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ALDH1A1 | P00352 | 5/20 | 0.43 |
| ▸ | RAB9A | P51151 | 3/20 | 0.43 |
| ▸ | HTT | P42858 | 3/20 | 0.43 |
| ▸ | MAPT | P10636 | 2/20 | 0.43 |
| ▸ | NPC1 | O15118 | 1/20 | 0.43 |
| ▸ | NR2F2 | P24468 | 1/20 | 0.43 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.43 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.43 |
| ▸ | PDE4B | Q07343 | 1/20 | 0.39 |
| ▸ | LMNA | P02545 | 3/20 | 0.38 |
| ▸ | MEN1 | O00255 | 2/20 | 0.38 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.38 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.38 |
| ▸ | THRB | P10828 | 1/20 | 0.38 |
| ▸ | HPGD | P15428 | 1/20 | 0.38 |
| ▸ | RECQL | P46063 | 1/20 | 0.38 |
| ▸ | HIF1A | Q16665 | 1/20 | 0.38 |
| ▸ | NPSR1 | Q6W5P4 | 3/20 | 0.38 |
| ▸ | CNR1 | P21554 | 1/20 | 0.38 |
| ▸ | CNR2 | P34972 | 1/20 | 0.38 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL9626830 | 1.00 | ALDH1A1 (0.43) | ALDH1A1RAB9AHTTMAPTNPC1 | |
| SCHEMBL9529540 | 0.73 | ALDH1A1 (0.51) | ALDH1A1RAB9AMAPTMAPK1MEN1 | |
| SCHEMBL9628596 | 0.73 | ALDH1A1 (0.51) | ALDH1A1RAB9AMAPTMAPK1MEN1 | |
| SCHEMBL9626837 | 0.73 | NPC1 (0.49) | ALDH1A1RAB9AHTTMAPTNPC1 | |
| SCHEMBL9528312 | 0.72 | NPC1 (0.39) | ALDH1A1RAB9AMAPTNPC1MAPK1 | |
| SCHEMBL9528535 | 0.72 | NPC1 (0.39) | ALDH1A1RAB9AMAPTNPC1MAPK1 | |
| SCHEMBL10453738 | 0.72 | NPC1 (0.39) | ALDH1A1RAB9AMAPTNPC1MAPK1 | |
| SCHEMBL9528543 | 0.72 | NPC1 (0.39) | ALDH1A1RAB9AMAPTNPC1MAPK1 | |
| SCHEMBL10453737 | 0.72 | NPC1 (0.39) | ALDH1A1RAB9AMAPTNPC1MAPK1 | |
| SCHEMBL9528315 | 0.72 | NPC1 (0.39) | ALDH1A1RAB9AMAPTNPC1MAPK1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0289430-B1 | SWEETENERS DERIVED FROM GUANIDINOACETIC AND ETHANAMIDINOACETIC ACIDS, THEIR USES AND COMPOSITIONS CONTAINING THESE SWEETENERS | UNIVERSITE CLAUDE BERNARD - LYON 1 (FR) | 1992-04-08 | — | — | EP | disclosed |
| EP-0289430-A1 | Sweeteners derived from guanidinoacetic and ethanamidinoacetic acids, their uses and compositions containing these sweeteners | UNIVERSITE CLAUDE BERNARD - LYON 1 (FR) | 1988-11-02 | — | — | EP | disclosed |