Predicted protein targets (top 15)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | CYP3A4 | P08684 | 1/20 | 0.34 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.33 |
| ▸ | GABBR2 | O75899 | 1/20 | 0.32 |
| ▸ | GABRB1 | P18505 | 1/20 | 0.32 |
| ▸ | GABRB2 | P47870 | 1/20 | 0.32 |
| ▸ | GABBR1 | Q9UBS5 | 1/20 | 0.32 |
| ▸ | BCHE | P06276 | 1/20 | 0.31 |
| ▸ | MGLL | Q99685 | 1/20 | 0.31 |
| ▸ | MEN1 | O00255 | 1/20 | 0.30 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.30 |
| ▸ | RAB9A | P51151 | 2/20 | 0.30 |
| ▸ | NPC1 | O15118 | 1/20 | 0.30 |
| ▸ | MAPT | P10636 | 1/20 | 0.30 |
| ▸ | HPGD | P15428 | 1/20 | 0.30 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.30 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL10894242 | 0.83 | MGLL (0.46) | MGLL | |
| SCHEMBL34195 | 0.80 | CYP3A4 (0.41) | CYP3A4CYP1A2MEN1KMT2AMAPT | |
| SCHEMBL196269 | 0.78 | CYP3A4 (0.43) | CYP3A4CYP1A2BCHEMAPTSMN1; SMN2 | |
| SCHEMBL2673413 | 0.78 | CYP3A4 (0.43) | CYP3A4CYP1A2BCHEMAPTSMN1; SMN2 | |
| SCHEMBL8675986 | 0.77 | MEN1 (0.47) | CYP3A4MEN1KMT2ARAB9ANPC1 | |
| SCHEMBL6686282 | 0.77 | MEN1 (0.42) | CYP3A4CYP1A2MEN1KMT2AMAPT | |
| Vinyl Chloride SCHEMBL9625391 | 0.77 | LMNA (0.39) | CYP3A4CYP1A2MEN1KMT2ARAB9A | |
| Butadiene SCHEMBL675872 | 0.77 | CYP3A4 (0.42) | CYP3A4CYP1A2BCHEMAPTSMN1; SMN2 | |
| Acrylonitrile SCHEMBL9249811 | 0.74 | LMNA (0.37) | CYP3A4CYP1A2MEN1KMT2AMAPT | |
| SCHEMBL10772380 | 0.74 | CYP1A2 (0.50) | CYP3A4CYP1A2BCHEMAPTSMN1; SMN2 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0274351-B1 | SUBSTITUTED 1,3,4-OXATHIAZOL-2-ONE STABILIZERS | CIBA-GEIGY AG (CH) | 1992-03-18 | — | — | EP | disclosed |