Predicted protein targets (top 17)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | MAPT | P10636 | 5/20 | 0.50 |
| ▸ | KDM4E | B2RXH2 | 4/20 | 0.50 |
| ▸ | ALDH1A1 | P00352 | 5/20 | 0.48 |
| ▸ | LMNA | P02545 | 3/20 | 0.48 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.48 |
| ▸ | GAA | P10253 | 1/20 | 0.42 |
| ▸ | IDO1 | P14902 | 2/20 | 0.41 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.41 |
| ▸ | MAOA | P21397 | 2/20 | 0.39 |
| ▸ | MAOB | P27338 | 2/20 | 0.39 |
| ▸ | NOX1 | Q9Y5S8 | 1/20 | 0.38 |
| ▸ | HPGD | P15428 | 1/20 | 0.38 |
| ▸ | DUSP3 | P51452 | 1/20 | 0.38 |
| ▸ | PTPN5 | P54829 | 1/20 | 0.38 |
| ▸ | PTPN11 | Q06124 | 1/20 | 0.38 |
| ▸ | APOBEC3G | Q9HC16 | 1/20 | 0.38 |
| ▸ | NPSR1 | Q6W5P4 | 1/20 | 0.38 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| 1,4-Dichlorobenzene SCHEMBL27669699 | 0.75 | MAPT (0.58) | MAPTKDM4EALDH1A1LMNAL3MBTL1 | |
| Chlorobenzene SCHEMBL9625713 | 0.74 | TSHR (0.41) | MAPTKDM4EALDH1A1LMNAL3MBTL1 | |
| 1,4-Dichlorobenzene SCHEMBL27808925 | 0.74 | LMNA (0.67) | LMNAIDO1SMN1; SMN2 | |
| Anisole SCHEMBL9625768 | 0.71 | CA4 (0.54) | MAPTALDH1A1GAASMN1; SMN2MAOB | |
| Chlorobenzene SCHEMBL27839844 | 0.70 | TSHR (0.52) | MAPTKDM4EALDH1A1LMNAGAA | |
| SCHEMBL1753791 | 0.70 | MAPT (0.56) | MAPTKDM4EALDH1A1LMNAL3MBTL1 | |
| SCHEMBL28117554 | 0.70 | IDO1 (0.47) | MAPTKDM4EALDH1A1LMNAL3MBTL1 | |
| 1,4-Dichlorobenzene SCHEMBL27966328 | 0.69 | KDM4E (0.60) | MAPTKDM4EALDH1A1LMNAL3MBTL1 | |
| 1,4-Dichlorobenzene SCHEMBL16107734 | 0.68 | LMNA (0.57) | MAPTKDM4EALDH1A1LMNAL3MBTL1 | |
| Benzene SCHEMBL27675941 | 0.68 | ALDH1A1 (0.47) | MAPTKDM4EALDH1A1LMNAGAA |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-5095024-A | Parasiticides | BAYER AKTIENGESELLSCHAFT (DE) | 1992-03-10 | — | — | US | disclosed |