Predicted protein targets (top 15)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | MAOB | P27338 | 8/20 | 0.70 |
| ▸ | FFAR1 | O14842 | 1/20 | 0.69 |
| ▸ | FFAR4 | Q5NUL3 | 1/20 | 0.69 |
| ▸ | LTA4H | P09960 | 1/20 | 0.62 |
| ▸ | EPHX2 | P34913 | 1/20 | 0.62 |
| ▸ | NR4A2 | P43354 | 2/20 | 0.62 |
| ▸ | MAPT | P10636 | 2/20 | 0.55 |
| ▸ | POLB | P06746 | 1/20 | 0.55 |
| ▸ | HTT | P42858 | 1/20 | 0.54 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.54 |
| ▸ | PDGFRA | P16234 | 1/20 | 0.54 |
| ▸ | S1PR1 | P21453 | 1/20 | 0.54 |
| ▸ | S1PR5 | Q9H228 | 1/20 | 0.54 |
| ▸ | MRGPRX4 | Q96LA9 | 2/20 | 0.52 |
| ▸ | IDO1 | P14902 | 1/20 | 0.50 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL23642800 | 0.96 | MAOB (0.68) | MAOBFFAR1FFAR4LTA4HEPHX2 | |
| SCHEMBL31676723 | 0.96 | MAOB (0.68) | MAOBFFAR1FFAR4LTA4HEPHX2 | |
| SCHEMBL6702238 | 0.85 | MAOB (0.65) | MAOBFFAR1FFAR4NR4A2MAPT | |
| SCHEMBL18003091 | 0.84 | LTA4H (0.67) | MAOBFFAR1FFAR4LTA4HEPHX2 | |
| SCHEMBL81305 | 0.82 | TAAR1 (0.62) | MAPTHTTIDO1 | |
| SCHEMBL18003261 | 0.81 | CYP4F2 (0.58) | MAOBFFAR1FFAR4LTA4HEPHX2 | |
| Bromide SCHEMBL28093819 | 0.81 | TAAR1 (0.61) | MAPTHTTIDO1 | |
| SCHEMBL23642870 | 0.80 | MAOB (0.64) | MAOBFFAR1FFAR4LTA4HEPHX2 | |
| SCHEMBL5669711 | 0.79 | MAOB (0.74) | MAOBFFAR1FFAR4NR4A2MAPT | |
| SCHEMBL9626584 | 0.79 | LTA4H (0.68) | MAOBLTA4HEPHX2NR4A2S1PR1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0477184-A1 | INHIBITORS OF MONO-AMINE OXIDASE, PROCESS FOR THEIR PREPARATION, AND THEIR USE IN THERAPEUTICS. | FOURNIER INDUSTRIE ET SANTE (FR) | 1992-04-01 | — | — | EP | disclosed |
| WO-1990011997-A2 | INHIBITORS OF MONO-AMINE OXIDASE, PROCESS FOR THEIR PREPARATION, AND THEIR USE IN THERAPEUTICS. | FOURNIER INNOVATION ET SYNERGIE (FR) | 1990-10-18 | — | — | WO | disclosed |