Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | TSHR | P16473 | 2/20 | 0.48 |
| ▸ | CYP1A2 | P05177 | 2/20 | 0.38 |
| ▸ | CYP3A4 | P08684 | 2/20 | 0.38 |
| ▸ | CYP2D6 | P10635 | 2/20 | 0.38 |
| ▸ | NFKB1 | P19838 | 2/20 | 0.38 |
| ▸ | PNMT | P11086 | 1/20 | 0.38 |
| ▸ | LMNA | P02545 | 3/20 | 0.37 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.37 |
| ▸ | GLA | P06280 | 1/20 | 0.37 |
| ▸ | SELPLG | Q14242 | 1/20 | 0.34 |
| ▸ | RORC | P51449 | 1/20 | 0.33 |
| ▸ | P2RX7 | Q99572 | 1/20 | 0.33 |
| ▸ | ESR1 | P03372 | 1/20 | 0.33 |
| ▸ | S1PR1 | P21453 | 1/20 | 0.33 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.33 |
| ▸ | HDAC4 | P56524 | 1/20 | 0.33 |
| ▸ | HDAC2 | Q92769 | 1/20 | 0.33 |
| ▸ | HDAC8 | Q9BY41 | 1/20 | 0.33 |
| ▸ | SCN4A | P35499 | 3/20 | 0.32 |
| ▸ | MAOA | P21397 | 2/20 | 0.32 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL2632877 | 0.82 | PNMT (0.59) | TSHRCYP1A2CYP3A4CYP2D6NFKB1 | |
| SCHEMBL27391011 | 0.79 | TSHR (0.52) | TSHRCYP1A2CYP3A4CYP2D6NFKB1 | |
| SCHEMBL2737288 | 0.79 | LMNA (0.46) | TSHRCYP1A2CYP3A4CYP2D6NFKB1 | |
| SCHEMBL5496564 | 0.79 | TSHR (0.61) | TSHRCYP2D6RORCESR1HTR2A | |
| SCHEMBL793225 | 0.79 | TSHR (0.61) | TSHRCYP2D6RORCESR1HTR2A | |
| SCHEMBL5357776 | 0.79 | TSHR (0.61) | TSHRCYP2D6RORCESR1HTR2A | |
| SCHEMBL29654913 | 0.79 | TSHR (0.61) | TSHRCYP2D6RORCESR1HTR2A | |
| SCHEMBL22871213 | 0.78 | TSHR (0.47) | TSHRCYP1A2CYP3A4CYP2D6NFKB1 | |
| SCHEMBL16957554 | 0.78 | CYP1A2 (0.33) | TSHRCYP1A2CYP3A4CYP2D6NFKB1 | |
| SCHEMBL22969911 | 0.78 | CYP1A2 (0.34) | TSHRCYP1A2CYP3A4CYP2D6NFKB1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 4 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-10357493-B2 | Metalloenzyme inhibitor compounds | SELENITY THERAPEUTICS (BERMUDA), LTD. (BM) | 2019-07-23 | — | — | US | disclosed |
| EP-0347690-B1 | PROCESS FOR MANUFACTURING BENZENE DERIVATIVES, AND BENZENE DERIVATIVES | BASF Aktiengesellschaft (DE) | 1992-10-21 | — | — | EP | disclosed |
| US-5151548-A | Crop protection agents | BASF AKTIENGESELLSCHAFT (DE) | 1992-09-29 | — | — | US | disclosed |
| EP-0347690-A2 | Process for manufacturing benzene derivatives, and benzene derivatives | BASF Aktiengesellschaft (DE) | 1989-12-27 | — | — | EP | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-10357493-B2 | Metalloenzyme inhibitor compounds | HDAC6, HDAC1, HDAC2 | TSHR 3249/4885CYP1A2 3515/4885CYP3A4 3953/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.