Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | NR3C1 | P04150 | 8/20 | 0.57 |
| ▸ | HIF1A | Q16665 | 6/20 | 0.57 |
| ▸ | LMNA | P02545 | 4/20 | 0.57 |
| ▸ | PGR | P06401 | 3/20 | 0.57 |
| ▸ | CYP3A4 | P08684 | 3/20 | 0.57 |
| ▸ | CYP2C9 | P11712 | 2/20 | 0.57 |
| ▸ | NR1I2 | O75469 | 1/20 | 0.57 |
| ▸ | GAA | P10253 | 1/20 | 0.57 |
| ▸ | HTT | P42858 | 1/20 | 0.57 |
| ▸ | HRH1 | P35367 | 1/20 | 0.55 |
| ▸ | AR | P10275 | 2/20 | 0.53 |
| ▸ | HSD17B10 | Q99714 | 2/20 | 0.53 |
| ▸ | TSHR | P16473 | 1/20 | 0.51 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.51 |
| ▸ | MEN1 | O00255 | 1/20 | 0.48 |
| ▸ | MAPT | P10636 | 1/20 | 0.48 |
| ▸ | CYP2C19 | P33261 | 1/20 | 0.48 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.48 |
| ▸ | FNTA | P49354 | 1/20 | 0.47 |
| ▸ | FNTB | P49356 | 1/20 | 0.47 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL9627979 | 1.00 | NR3C1 (0.57) | NR3C1HIF1ALMNAPGRCYP3A4 | |
| SCHEMBL13069286 | 0.90 | NR3C1 (0.67) | NR3C1HIF1ALMNAPGRCYP3A4 | |
| SCHEMBL13069231 | 0.90 | NR3C1 (0.67) | NR3C1HIF1ALMNAPGRCYP3A4 | |
| SCHEMBL11854050 | 0.90 | NR3C1 (0.72) | NR3C1HIF1APGRCYP3A4HRH1 | |
| SCHEMBL11854066 | 0.90 | NR3C1 (0.72) | NR3C1HIF1APGRCYP3A4HRH1 | |
| SCHEMBL13069234 | 0.89 | NR3C1 (0.55) | NR3C1HIF1ALMNAPGRCYP3A4 | |
| SCHEMBL4273345 | 0.83 | AR (0.54) | NR3C1HIF1ALMNAPGRCYP3A4 | |
| SCHEMBL4267312 | 0.83 | AR (0.54) | NR3C1HIF1ALMNAPGRCYP3A4 | |
| SCHEMBL4267316 | 0.83 | AR (0.54) | NR3C1HIF1ALMNAPGRCYP3A4 | |
| SCHEMBL21231580 | 0.83 | NR3C1 (0.80) | NR3C1HIF1ALMNAPGRCYP3A4 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0276393-B1 | PROCESS FOR THE PREPARATION OF 6-ALPHA, 9-ALPHA-DIFLUORO-11-BETA-17-ALPHA-DIHYDROXY-16-ALPHA-METHYL-PREGN-4-ENE-3,20-DIONE AND ITS DERIVATIVES | SCHERING AKTIENGESELLSCHAFT (DE) | 1992-03-04 | — | — | EP | claimed |
| EP-0276393-B1 | PROCESS FOR THE PREPARATION OF 6-ALPHA, 9-ALPHA-DIFLUORO-11-BETA-17-ALPHA-DIHYDROXY-16-ALPHA-METHYL-PREGN-4-ENE-3,20-DIONE AND ITS DERIVATIVES | SCHERING AKTIENGESELLSCHAFT (DE) | 1992-03-04 | — | — | EP | disclosed |