SCHEMBL9628007

SCHEMBL9628007

S=c1sc2ccccc2n1CN1CCOCC1

nearest known ligand 0.49

Predicted protein targets (top 17)

geneUniProtsupporting neighboursconfidence
MAPT P10636 3/20 0.46
KDM4E B2RXH2 2/20 0.46
TSHR P16473 1/20 0.46
ALOX12 P18054 1/20 0.46
L3MBTL1 Q9Y468 1/20 0.46
DRD2 P14416 1/20 0.45
SLC6A4 P31645 1/20 0.45
SLC6A3 Q01959 1/20 0.45
CYP2D6 P10635 1/20 0.43
TP53 P04637 1/20 0.41
MAPK1 P28482 1/20 0.41
HTT P42858 1/20 0.41
ATM Q13315 1/20 0.41
ALDH1A1 P00352 2/20 0.41
CYP1A2 P05177 1/20 0.40
HPGD P15428 1/20 0.40
HSD17B10 Q99714 1/20 0.40

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL9629816 0.89 DRD2 (0.53) DRD2SLC6A4SLC6A3ALDH1A1CYP1A2
SCHEMBL9628249 0.86 DRD2 (0.51) DRD2SLC6A4SLC6A3ALDH1A1CYP1A2
SCHEMBL9627998 0.85 DRD2 (0.53) DRD2SLC6A4SLC6A3ALDH1A1CYP1A2
SCHEMBL961938 0.73 F12 (0.50) TSHR
SCHEMBL29540464 0.73 MAPT (0.75) MAPTKDM4ETSHRALOX12L3MBTL1
SCHEMBL148312 0.73 MAPT (0.75) MAPTKDM4ETSHRALOX12L3MBTL1
SCHEMBL3393854 0.71 ALDH1A1 (0.48) MAPTKDM4ETSHRL3MBTL1DRD2
SCHEMBL8079249 0.71 ALDH1A1 (0.51) KDM4ETSHRL3MBTL1DRD2SLC6A4
SCHEMBL513869 0.71 ALDH1A1 (0.48) MAPTKDM4ETSHRL3MBTL1DRD2
SCHEMBL19499953 0.71 DRD2 (0.48) L3MBTL1DRD2SLC6A4SLC6A3HTT

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 6 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
EP-0203033-B1 AMINO ETHYL DERIVATIVE OF BENZOTHIAZOLINTHION AS A LUBRICANT ADDITIVE CIBA-GEIGY AG (CH) 1992-03-11 EP disclosed
US-4810399-A FRICTION, WEAR, CORROSION AND OXIDATION RESISTANCE CIBA-GEIGY CORPORATION (US) 1989-03-07 US disclosed
EP-0137223-B1 PHOTOGRAPHIC IMAGE-RECEIVING ELEMENT FOR SILVER SALT DIFFUSION TRANSFER PROCESS FUJI PHOTO FILM CO., LTD. (JP) 1988-05-11 EP disclosed
US-4737302-A Aminomethyl derivatives of benzothiazolinethione as lubricant additives CIBA-GEIGY CORPORATION (US) 1988-04-12 US disclosed
US-4585725-A STORAGE STABILITY FUJI PHOTO FILM CO., LTD. (JP) 1986-04-29 US disclosed
EP-0137223-A2 Photographic image-receiving element for silver salt diffusion transfer process FUJI PHOTO FILM CO., LTD. (JP) 1985-04-17 EP disclosed