⚠ Novel chemotype — no close known analogue (best Tanimoto < 0.3). Unexplored chemical space relative to ChEMBL.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL18905807 | 0.91 | NPSR1 (0.31) | — | |
| SCHEMBL25841428 | 0.88 | LMNA (0.30) | — | |
| SCHEMBL28510380 | 0.79 | — | — | |
| SCHEMBL21238187 | 0.78 | — | — | |
| SCHEMBL18905813 | 0.78 | EPHX2 (0.34) | — | |
| SCHEMBL31623216 | 0.76 | — | — | |
| SCHEMBL5156638 | 0.76 | CYP4F2 (0.31) | — | |
| SCHEMBL2278073 | 0.74 | FFAR3 (0.40) | — | |
| SCHEMBL25718014 | 0.74 | SLC6A2 (0.33) | — | |
| SCHEMBL25259309 | 0.74 | — | — |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 6 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-20250122196-A1 | FGFR3 INHIBITOR COMPOUNDS | ELI LILLY AND COMPANY | 2025-04-17 | — | — | US | disclosed |
| US-12209086-B2 | FGFR3 inhibitor compounds | ELI LILLY AND COMPANY (US) | 2025-01-28 | — | — | US | disclosed |
| US-20240190870-A1 | FGFR3 INHIBITOR COMPOUNDS | LOXO ONCOLOGY, INC. | 2024-06-13 | — | — | US | disclosed |
| US-11878976-B2 | FGFR3 inhibitor compounds | ELI LILLY AND COMPANY (US) | 2024-01-23 | — | — | US | disclosed |
| US-20230095122-A1 | FGFR3 INHIBITOR COMPOUNDS | LOXO ONCOLOGY, INC. | 2023-03-30 | — | — | US | disclosed |
| US-5140035-A | FUNGICIDAL TRIAZOLYMETHYL-CYCLOPROPYL DERIVATIVES | BAYER AKTIENGESELLSCHAFT (DE) | 1992-08-18 | — | — | US | disclosed |