Predicted protein targets (top 4)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | SLC6A2 | P23975 | 1/20 | 0.33 |
| ▸ | SLC6A4 | P31645 | 1/20 | 0.33 |
| ▸ | SLC6A3 | Q01959 | 1/20 | 0.33 |
| ▸ | OPRM1 | P35372 | 1/20 | 0.32 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL9628016 | 0.74 | — | — | |
| SCHEMBL28849860 | 0.72 | NPSR1 (0.33) | SLC6A2SLC6A4SLC6A3OPRM1 | |
| SCHEMBL25083898 | 0.71 | FFAR3 (0.40) | SLC6A2SLC6A4SLC6A3OPRM1 | |
| SCHEMBL6222743 | 0.70 | SLC6A2 (0.38) | SLC6A2SLC6A4SLC6A3OPRM1 | |
| SCHEMBL23469868 | 0.70 | SLC6A2 (0.38) | SLC6A2SLC6A4SLC6A3OPRM1 | |
| SCHEMBL6222739 | 0.67 | OPRK1 (0.46) | SLC6A2SLC6A4SLC6A3OPRM1 | |
| SCHEMBL18905807 | 0.67 | NPSR1 (0.31) | — | |
| SCHEMBL6203664 | 0.65 | ALDH1A1 (0.40) | SLC6A4OPRM1 | |
| SCHEMBL8290930 | 0.64 | — | — | |
| SCHEMBL1468175 | 0.64 | — | — |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-20230183214-A1 | IL4I1 INHIBITORS AND METHODS OF USE | MERCK SHARP & DOHME LLC | 2023-06-15 | — | — | US | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20230183214-A1 | IL4I1 INHIBITORS AND METHODS OF USE | IL4I1, IL4, IL2 | SLC6A2 4033/4885SLC6A4 1787/4885SLC6A3 4388/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.