Predicted protein targets (top 9)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | POLB | P06746 | 1/20 | 0.53 |
| ▸ | AOC3 | Q16853 | 1/20 | 0.50 |
| ▸ | NPY1R | P25929 | 9/20 | 0.49 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.48 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.48 |
| ▸ | TSHR | P16473 | 1/20 | 0.45 |
| ▸ | HPGD | P15428 | 1/20 | 0.44 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.43 |
| ▸ | UNG | P13051 | 3/20 | 0.43 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL9628458 | 1.00 | POLB (0.53) | POLBAOC3NPY1RKMT2ASMN1; SMN2 | |
| SCHEMBL9628556 | 1.00 | POLB (0.53) | POLBAOC3NPY1RKMT2ASMN1; SMN2 | |
| SCHEMBL9629111 | 0.99 | POLB (0.54) | POLBAOC3NPY1RKMT2ASMN1; SMN2 | |
| SCHEMBL9629092 | 0.94 | POLB (0.55) | POLBAOC3NPY1RKMT2ASMN1; SMN2 | |
| SCHEMBL9628581 | 0.84 | POLB (0.51) | POLBNPY1RKMT2ASMN1; SMN2HPGD | |
| SCHEMBL2391508 | 0.77 | ESR1 (0.61) | ALDH1A1UNG | |
| SCHEMBL60027 | 0.77 | ESR1 (0.61) | ALDH1A1UNG | |
| SCHEMBL294666 | 0.77 | ESR1 (0.61) | ALDH1A1UNG | |
| SCHEMBL9330410 | 0.77 | ESR1 (0.61) | ALDH1A1UNG | |
| SCHEMBL284616 | 0.77 | ESR1 (0.61) | ALDH1A1UNG |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 6 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0279398-B1 | ANTIFUNGAL 2-ANILINOTHIAZOLINES | MERRELL DOW PHARMACEUTICALS INC. (US) | 1992-03-18 | — | — | EP | claimed |
| US-4788209-A | INFECTIONS OF SKIN AND MUCOUS MEMBRANES | MERRELL DOW PHARMACEUTICALS INC. (US) | 1988-11-29 | — | — | US | claimed |
| EP-0279398-A1 | Antifungal 2-anilinothiazolines | MERRELL DOW PHARMACEUTICALS INC. (US) | 1988-08-24 | — | — | EP | claimed |
| EP-0279398-B1 | ANTIFUNGAL 2-ANILINOTHIAZOLINES | MERRELL DOW PHARMACEUTICALS INC. (US) | 1992-03-18 | — | — | EP | disclosed |
| US-4788209-A | INFECTIONS OF SKIN AND MUCOUS MEMBRANES | MERRELL DOW PHARMACEUTICALS INC. (US) | 1988-11-29 | — | — | US | disclosed |
| EP-0279398-A1 | Antifungal 2-anilinothiazolines | MERRELL DOW PHARMACEUTICALS INC. (US) | 1988-08-24 | — | — | EP | disclosed |