Predicted protein targets (top 16)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | POLB | P06746 | 1/20 | 0.51 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.43 |
| ▸ | HPGD | P15428 | 1/20 | 0.43 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.43 |
| ▸ | LPL | P06858 | 2/20 | 0.41 |
| ▸ | LIPG | Q9Y5X9 | 2/20 | 0.41 |
| ▸ | NPY1R | P25929 | 2/20 | 0.41 |
| ▸ | S1PR4 | O95977 | 2/20 | 0.40 |
| ▸ | S1PR1 | P21453 | 2/20 | 0.40 |
| ▸ | S1PR5 | Q9H228 | 2/20 | 0.40 |
| ▸ | S1PR3 | Q99500 | 1/20 | 0.40 |
| ▸ | ATM | Q13315 | 1/20 | 0.39 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.39 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.39 |
| ▸ | HSD17B10 | Q99714 | 1/20 | 0.39 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.39 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL9628458 | 0.84 | POLB (0.53) | POLBSMN1; SMN2HPGDALDH1A1NPY1R | |
| SCHEMBL9628556 | 0.84 | POLB (0.53) | POLBSMN1; SMN2HPGDALDH1A1NPY1R | |
| SCHEMBL9628041 | 0.84 | POLB (0.53) | POLBSMN1; SMN2HPGDALDH1A1NPY1R | |
| SCHEMBL9629111 | 0.83 | POLB (0.54) | POLBSMN1; SMN2HPGDALDH1A1NPY1R | |
| SCHEMBL9418466 | 0.79 | LPL (0.56) | LPLLIPGS1PR4S1PR1S1PR5 | |
| SCHEMBL29767685 | 0.79 | LPL (0.56) | LPLLIPGS1PR4S1PR1S1PR5 | |
| SCHEMBL11871771 | 0.79 | LPL (0.56) | LPLLIPGS1PR4S1PR1S1PR5 | |
| SCHEMBL9629092 | 0.79 | POLB (0.55) | POLBSMN1; SMN2HPGDALDH1A1NPY1R | |
| SCHEMBL24244461 | 0.75 | LPL (0.51) | ALDH1A1LPLLIPGS1PR4S1PR1 | |
| SCHEMBL20921417 | 0.75 | LPL (0.51) | ALDH1A1LPLLIPGS1PR4S1PR1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0279398-B1 | ANTIFUNGAL 2-ANILINOTHIAZOLINES | MERRELL DOW PHARMACEUTICALS INC. (US) | 1992-03-18 | — | — | EP | disclosed |
| US-4788209-A | INFECTIONS OF SKIN AND MUCOUS MEMBRANES | MERRELL DOW PHARMACEUTICALS INC. (US) | 1988-11-29 | — | — | US | disclosed |
| EP-0279398-A1 | Antifungal 2-anilinothiazolines | MERRELL DOW PHARMACEUTICALS INC. (US) | 1988-08-24 | — | — | EP | disclosed |