Predicted protein targets (top 16)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | POLB | P06746 | 1/20 | 0.55 |
| ▸ | AOC3 | Q16853 | 1/20 | 0.52 |
| ▸ | NPY1R | P25929 | 11/20 | 0.51 |
| ▸ | SMN1; SMN2 | Q16637 | 2/20 | 0.50 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.50 |
| ▸ | TSHR | P16473 | 1/20 | 0.47 |
| ▸ | HPGD | P15428 | 2/20 | 0.46 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.45 |
| ▸ | NPC1 | O15118 | 1/20 | 0.44 |
| ▸ | CASP3 | P42574 | 1/20 | 0.44 |
| ▸ | RAB9A | P51151 | 1/20 | 0.44 |
| ▸ | NPSR1 | Q6W5P4 | 1/20 | 0.44 |
| ▸ | SENP8 | Q96LD8 | 1/20 | 0.44 |
| ▸ | SENP7 | Q9BQF6 | 1/20 | 0.44 |
| ▸ | SENP6 | Q9GZR1 | 1/20 | 0.44 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.44 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL9629111 | 0.96 | POLB (0.54) | POLBAOC3NPY1RSMN1; SMN2KMT2A | |
| SCHEMBL9628458 | 0.94 | POLB (0.53) | POLBAOC3NPY1RSMN1; SMN2KMT2A | |
| SCHEMBL9628041 | 0.94 | POLB (0.53) | POLBAOC3NPY1RSMN1; SMN2KMT2A | |
| SCHEMBL9628556 | 0.94 | POLB (0.53) | POLBAOC3NPY1RSMN1; SMN2KMT2A | |
| SCHEMBL9628581 | 0.79 | POLB (0.51) | POLBNPY1RSMN1; SMN2KMT2AHPGD | |
| SCHEMBL3545384 | 0.75 | POLB (0.57) | POLBAOC3NPY1RSMN1; SMN2KMT2A | |
| SCHEMBL48879 | 0.75 | HPGD (0.58) | POLBSMN1; SMN2KMT2AHPGDALDH1A1 | |
| SCHEMBL14127779 | 0.75 | HPGD (0.58) | POLBSMN1; SMN2KMT2AHPGDALDH1A1 | |
| SCHEMBL8934607 | 0.74 | AOC3 (0.47) | POLBAOC3NPY1RKMT2ATSHR | |
| SCHEMBL8934611 | 0.73 | POLB (0.48) | POLBAOC3NPY1RHPGD |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0279398-B1 | ANTIFUNGAL 2-ANILINOTHIAZOLINES | MERRELL DOW PHARMACEUTICALS INC. (US) | 1992-03-18 | — | — | EP | disclosed |
| US-4788209-A | INFECTIONS OF SKIN AND MUCOUS MEMBRANES | MERRELL DOW PHARMACEUTICALS INC. (US) | 1988-11-29 | — | — | US | disclosed |
| EP-0279398-A1 | Antifungal 2-anilinothiazolines | MERRELL DOW PHARMACEUTICALS INC. (US) | 1988-08-24 | — | — | EP | disclosed |