Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | MAPT | P10636 | 3/20 | 0.41 |
| ▸ | NCF1 | P14598 | 2/20 | 0.40 |
| ▸ | NOS2 | P35228 | 1/20 | 0.40 |
| ▸ | BACE1 | P56817 | 1/20 | 0.40 |
| ▸ | NPC1 | O15118 | 3/20 | 0.39 |
| ▸ | RAB9A | P51151 | 3/20 | 0.39 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.39 |
| ▸ | CYP3A4 | P08684 | 2/20 | 0.39 |
| ▸ | MEN1 | O00255 | 2/20 | 0.39 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.39 |
| ▸ | TP53 | P04637 | 1/20 | 0.39 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.39 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.39 |
| ▸ | HIF1A | Q16665 | 1/20 | 0.39 |
| ▸ | GAA | P10253 | 1/20 | 0.39 |
| ▸ | CYP1A2 | P05177 | 2/20 | 0.36 |
| ▸ | CA12 | O43570 | 1/20 | 0.36 |
| ▸ | CA9 | Q16790 | 1/20 | 0.36 |
| ▸ | MGAM | O43451 | 1/20 | 0.36 |
| ▸ | LMNA | P02545 | 1/20 | 0.35 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL19386131 | 0.75 | PDE10A (0.47) | NCF1NOS2BACE1CYP3A4CYP1A2 | |
| SCHEMBL31463622 | 0.73 | PIK3CD (0.43) | MAPTNPC1RAB9AALDH1A1KMT2A | |
| SCHEMBL3390064 | 0.73 | PIK3CD (0.43) | MAPTNPC1RAB9AALDH1A1KMT2A | |
| SCHEMBL17713565 | 0.72 | HRH1 (0.51) | MAPTNCF1NOS2BACE1CYP3A4 | |
| SCHEMBL4866792 | 0.70 | HRH1 (0.49) | MAPTNCF1NOS2BACE1CYP3A4 | |
| SCHEMBL8354538 | 0.70 | TLR8 (0.45) | MAPTNPC1RAB9AALDH1A1KMT2A | |
| Putrescine SCHEMBL5357478 | 0.68 | NCF1 (0.50) | MAPTNCF1NOS2BACE1NPC1 | |
| SCHEMBL2305245 | 0.67 | PDE10A (0.50) | NCF1NOS2BACE1NPC1RAB9A | |
| SCHEMBL30285321 | 0.67 | PDE10A (0.50) | NCF1NOS2BACE1NPC1RAB9A | |
| SCHEMBL31542516 | 0.67 | PIK3CD (0.41) | MAPTNPC1RAB9AALDH1A1KMT2A |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-5098901-A | Cardiovascular disorders | STERLING DRUG INC. (US) | 1992-03-24 | — | — | US | disclosed |