Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | HTT | P42858 | 3/20 | 0.57 |
| ▸ | KDM4E | B2RXH2 | 4/20 | 0.43 |
| ▸ | HSD17B10 | Q99714 | 3/20 | 0.43 |
| ▸ | MAPT | P10636 | 2/20 | 0.43 |
| ▸ | TP53 | P04637 | 1/20 | 0.43 |
| ▸ | GAA | P10253 | 1/20 | 0.43 |
| ▸ | TSHR | P16473 | 3/20 | 0.41 |
| ▸ | SLC22A6 | Q4U2R8 | 1/20 | 0.38 |
| ▸ | TOP1 | P11387 | 1/20 | 0.38 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.38 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.38 |
| ▸ | PTGS2 | P35354 | 3/20 | 0.37 |
| ▸ | POLB | P06746 | 1/20 | 0.36 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.36 |
| ▸ | DHODH | Q02127 | 2/20 | 0.36 |
| ▸ | HPGD | P15428 | 2/20 | 0.36 |
| ▸ | ESR1 | P03372 | 1/20 | 0.36 |
| ▸ | ITGB3 | P05106 | 1/20 | 0.36 |
| ▸ | ITGA2B | P08514 | 1/20 | 0.36 |
| ▸ | HMGB1 | P09429 | 1/20 | 0.36 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL9627986 | 0.90 | HTT (0.55) | HTTKDM4EHSD17B10MAPTTP53 | |
| SCHEMBL9627634 | 0.86 | HTT (0.63) | HTTKDM4EHSD17B10MAPTTP53 | |
| SCHEMBL9713401 | 0.85 | ABCB11 (0.51) | HTTKDM4EHSD17B10MAPTTP53 | |
| SCHEMBL7918996 | 0.82 | HTT (0.75) | HTTKDM4EHSD17B10MAPTTP53 | |
| SCHEMBL9628598 | 0.80 | HTT (0.63) | HTTKDM4EHSD17B10MAPTTP53 | |
| SCHEMBL9628221 | 0.80 | HTT (0.58) | HTTKDM4EHSD17B10MAPTTP53 | |
| SCHEMBL23535401 | 0.79 | HTT (0.57) | HTTKDM4EHSD17B10MAPTTP53 | |
| SCHEMBL9627465 | 0.78 | HTT (0.69) | HTTKDM4EHSD17B10MAPTTP53 | |
| SCHEMBL9627873 | 0.78 | HTT (0.60) | HTTKDM4EHSD17B10MAPTTP53 | |
| SCHEMBL23271992 | 0.77 | HTT (0.67) | HTTKDM4EHSD17B10MAPTTP53 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-5089657-A | Topical antiinflammatory agents | SYNTEX (U.S.A.) INC. (US) | 1992-02-18 | — | — | US | disclosed |
| EP-0282056-A2 | Naphthalene anti-psoriatic agents | SYNTEX (U.S.A.) INC. (US) | 1988-09-14 | — | — | EP | disclosed |