Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ABCB11 | O95342 | 1/20 | 0.51 |
| ▸ | HTT | P42858 | 3/20 | 0.40 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.36 |
| ▸ | DHODH | Q02127 | 2/20 | 0.35 |
| ▸ | ALDH1A1 | P00352 | 3/20 | 0.35 |
| ▸ | KDM4E | B2RXH2 | 4/20 | 0.35 |
| ▸ | MAPT | P10636 | 2/20 | 0.35 |
| ▸ | MEN1 | O00255 | 1/20 | 0.35 |
| ▸ | LMNA | P02545 | 1/20 | 0.35 |
| ▸ | POLB | P06746 | 1/20 | 0.35 |
| ▸ | HPGD | P15428 | 1/20 | 0.35 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.35 |
| ▸ | NPSR1 | Q6W5P4 | 1/20 | 0.35 |
| ▸ | KDM5A | P29375 | 1/20 | 0.35 |
| ▸ | KDM4C | Q9H3R0 | 1/20 | 0.35 |
| ▸ | KDM5B | Q9UGL1 | 1/20 | 0.35 |
| ▸ | TSHR | P16473 | 1/20 | 0.34 |
| ▸ | HTR2A | P28223 | 1/20 | 0.34 |
| ▸ | HTR2C | P28335 | 1/20 | 0.34 |
| ▸ | HTR2B | P41595 | 1/20 | 0.34 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL9643015 | 0.85 | ABCB11 (0.63) | ABCB11HTTSMN1; SMN2DHODHALDH1A1 | |
| SCHEMBL9628228 | 0.85 | HTT (0.57) | HTTSMN1; SMN2DHODHALDH1A1KDM4E | |
| SCHEMBL9628176 | 0.82 | ABCB11 (0.56) | ABCB11HTTSMN1; SMN2ALDH1A1KDM4E | |
| SCHEMBL9643064 | 0.81 | ABCB11 (0.54) | ABCB11HTTSMN1; SMN2DHODHALDH1A1 | |
| SCHEMBL9629306 | 0.80 | ABCB11 (0.68) | ABCB11HTTSMN1; SMN2ALDH1A1KDM4E | |
| SCHEMBL9713395 | 0.79 | ABCB11 (0.52) | ABCB11HTTSMN1; SMN2ALDH1A1KDM4E | |
| SCHEMBL9713667 | 0.79 | ABCB11 (0.65) | ABCB11HTTSMN1; SMN2ALDH1A1KDM4E | |
| SCHEMBL9642690 | 0.78 | ABCB11 (0.54) | ABCB11HTTSMN1; SMN2DHODHALDH1A1 | |
| SCHEMBL10337090 | 0.78 | ABCB11 (0.54) | ABCB11HTTSMN1; SMN2DHODHALDH1A1 | |
| SCHEMBL9642245 | 0.78 | ABCB11 (0.54) | ABCB11HTTSMN1; SMN2DHODHALDH1A1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-5091558-A | Topical administeration | SYNTEX (U.S.A.) INC. (US) | 1992-02-25 | — | — | US | disclosed |
| EP-0150831-B1 | NAPHTHALENE ANTI-PSORIATIC AGENTS | SYNTEX (U.S.A.) INC. (US) | 1988-08-10 | — | — | EP | disclosed |
| EP-0150831-A2 | Naphthalene anti-psoriatic agents | SYNTEX (U.S.A.) INC. (US) | 1985-08-07 | — | — | EP | disclosed |