Predicted protein targets (top 19)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | MEN1 | O00255 | 1/20 | 0.51 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.51 |
| ▸ | ATM | Q13315 | 1/20 | 0.51 |
| ▸ | APP | P05067 | 1/20 | 0.40 |
| ▸ | ALDH1A1 | P00352 | 8/20 | 0.39 |
| ▸ | RAB9A | P51151 | 4/20 | 0.39 |
| ▸ | SMN1; SMN2 | Q16637 | 4/20 | 0.39 |
| ▸ | NPC1 | O15118 | 3/20 | 0.39 |
| ▸ | GAA | P10253 | 2/20 | 0.39 |
| ▸ | MAPT | P10636 | 2/20 | 0.39 |
| ▸ | L3MBTL1 | Q9Y468 | 2/20 | 0.39 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.39 |
| ▸ | LMNA | P02545 | 2/20 | 0.38 |
| ▸ | FFAR2 | O15552 | 1/20 | 0.38 |
| ▸ | KDM4E | B2RXH2 | 3/20 | 0.37 |
| ▸ | ALOX15 | P16050 | 1/20 | 0.36 |
| ▸ | HSD17B10 | Q99714 | 1/20 | 0.36 |
| ▸ | HPGD | P15428 | 1/20 | 0.36 |
| ▸ | TP53 | P04637 | 1/20 | 0.35 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL27339252 | 0.74 | DRD2 (0.43) | ALDH1A1MAPTMAPK1LMNA | |
| SCHEMBL13744743 | 0.73 | TDP1 (0.47) | MEN1KMT2AATMALDH1A1RAB9A | |
| SCHEMBL25746607 | 0.71 | MAPT (0.62) | MEN1KMT2AATMALDH1A1RAB9A | |
| SCHEMBL25746618 | 0.71 | MAPT (0.62) | MEN1KMT2AATMALDH1A1RAB9A | |
| SCHEMBL14114237 | 0.70 | TAAR1 (0.39) | MEN1KMT2AALDH1A1RAB9ANPC1 | |
| SCHEMBL4415965 | 0.68 | HTR2B (0.43) | MEN1KMT2AALDH1A1RAB9ASMN1; SMN2 | |
| SCHEMBL27995807 | 0.67 | APP (0.46) | MEN1KMT2AATMAPPALDH1A1 | |
| SCHEMBL8057572 | 0.67 | NOS3 (0.57) | MEN1KMT2AATM | |
| SCHEMBL16203066 | 0.67 | MEN1 (0.43) | MEN1KMT2AALDH1A1RAB9ASMN1; SMN2 | |
| SCHEMBL5993630 | 0.66 | HDAC3 (0.40) | ALDH1A1RAB9ASMN1; SMN2NPC1MAPT |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 5 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-1024794-C | Oxa-or thia-zoline derivative and preparaiton thereof | YASHIMA KAGAKU KOGYO KK (JP) | 1994-06-01 | — | — | CN | disclosed |
| EP-0345775-B1 | OXA- OR THIA-ZOLINE DERIVATIVE | YASHIMA CHEMICAL INDUSTRIAL CO., LTD. (JP) | 1992-04-08 | — | — | EP | disclosed |
| US-4977171-A | INSECTICIDES | YASHIMA CHEMICAL INDUSTRIAL CO., LTD. (JP) | 1990-12-11 | — | — | US | disclosed |
| CN-1038809-A | azoles quinoline or thiazoline derivative and its method for making | YASHIMA KAGAKU KOGYO KK (JP) | 1990-01-17 | — | — | CN | disclosed |
| EP-0345775-A1 | Oxa- or thia-zoline derivative | YASHIMA CHEMICAL INDUSTRIAL CO., LTD. (JP) | 1989-12-13 | — | — | EP | disclosed |