SCHEMBL9628291

SCHEMBL9628291

Nc1ccc(Cc2ccc(N)cc2S(=O)(=O)O)c(S(=O)(=O)O)c1

nearest known ligand 0.50

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
RAPGEF4 Q8WZA2 1/20 0.50
ALDH1A1 P00352 6/20 0.47
TDP1 Q9NUW8 4/20 0.47
GAA P10253 3/20 0.47
MAPT P10636 3/20 0.47
RECQL P46063 3/20 0.47
CASP6 P55212 3/20 0.47
L3MBTL1 Q9Y468 3/20 0.47
KDM4E B2RXH2 2/20 0.47
POLB P06746 2/20 0.47
NSD2 O96028 2/20 0.47
APEX1 P27695 1/20 0.47
APOBEC3A P31941 1/20 0.47
APOBEC3G Q9HC16 1/20 0.47
MEN1 O00255 2/20 0.45
KMT2A Q03164 2/20 0.45
ELAVL1 Q15717 1/20 0.45
TSHR P16473 4/20 0.43
NT5E P21589 3/20 0.43
HSD17B10 Q99714 5/20 0.42

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL29399463 1.00 RAPGEF4 (0.50) RAPGEF4ALDH1A1TDP1GAAMAPT
Ammonia Solution, Strong SCHEMBL7550166 0.98 RAPGEF4 (0.49) RAPGEF4ALDH1A1TDP1GAAMAPT
Trimethylammonium SCHEMBL7550079 0.93 RAPGEF4 (0.45) RAPGEF4ALDH1A1TDP1GAAMAPT
SCHEMBL14091805 0.90 ALDH1A1 (0.52) RAPGEF4ALDH1A1TDP1GAAMAPT
SCHEMBL7547998 0.88 PRKCI (0.46) RAPGEF4ALDH1A1TDP1GAAMAPT
SCHEMBL29963180 0.88 RAPGEF4 (0.50) RAPGEF4ALDH1A1TDP1GAAMAPT
SCHEMBL6427620 0.88 RAPGEF4 (0.50) RAPGEF4ALDH1A1TDP1GAAMAPT
SCHEMBL157161 0.86 RAPGEF4 (0.49) RAPGEF4ALDH1A1TDP1GAAMAPT
SCHEMBL7718118 0.86 RAPGEF4 (0.49) RAPGEF4ALDH1A1TDP1GAAMAPT
SCHEMBL26895312 0.86 RAPGEF4 (0.49) RAPGEF4ALDH1A1TDP1GAAMAPT

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 20 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
CN-104805675-A Decolorizing agent SHANGHAI PENGGANG IND DEV CO LTD 2015-07-29 CN disclosed
CN-104726237-A Yellow-spot-removing dry cleaning agent SHANGHAI PENGGANG IND DEV CO LTD 2015-06-24 CN disclosed
CN-104726236-A Degreasing emulsifier SHANGHAI PENGGANG IND DEV CO LTD 2015-06-24 CN disclosed
CN-104694280-A Oil-paint-removing dry cleaning agent SHANGHAI PENGGANG IND DEV CO LTD 2015-06-10 CN disclosed
EP-0260806-B1 COLORATION PROCESS IMPERIAL CHEMICAL INDUSTRIES PLC (GB) 1992-04-08 EP disclosed
US-4881942-A HEATING, FIXING, CONTROLLING PH TO 5.8 TO 8.0 IMPERIAL CHEMICAL INDUSTRIES PLC (GB) 1989-11-21 US disclosed
EP-0102752-B1 POLYAMIDE OF DISULFONATED DIAMINE AND PERMSELECTIVE MEMBRANE THEREOF E.I. DU PONT DE NEMOURS AND COMPANY (US) 1986-04-23 EP disclosed
EP-0138303-A1 Naphthalene sulphonic acids IMPERIAL CHEMICAL INDUSTRIES PLC (GB) 1985-04-24 EP disclosed
US-4471110-A REVERSE OSMOSIS E. I. DUPONT DE NEMOURS AND COMPANY (US) 1984-09-11 US disclosed
EP-0102752-A1 Polyamide of disulfonated diamine and permselective membrane thereof E.I. DU PONT DE NEMOURS AND COMPANY (US) 1984-03-14 EP disclosed
EP-0090114-A2 Reactive dyes IMPERIAL CHEMICAL INDUSTRIES PLC (GB) 1983-10-05 EP disclosed
EP-0066714-A2 Reactive dyestuffs BASF Aktiengesellschaft (DE) 1982-12-15 EP disclosed
US-4325887-A Isocyanatoaryl sulfonic acid esters BAYER AKTIENGESELLSCHAFT (DE) 1982-04-20 US disclosed
US-4300902-A Coloration process IMPERIAL CHEMICAL INDUSTRIES LIMITED (GB) 1981-11-17 US disclosed
EP-0001451-B1 WATER-SOLUBLE AZO-PHTHALOCYANINE FIBRE-REACTIVE DYESTUFFS, THEIR PREPARATION AND THEIR USE CASSELLA Aktiengesellschaft (DE) 1981-09-23 EP disclosed
US-4259255-A ISOCYANATOARYL SULFONATES BAYER AKTIENGESELLSCHAFT (DE) 1981-03-31 US disclosed
US-4204056-A Process and intermediates for preparing fiber-reactive phthalocyanine dyes CASSELLA AKTIENGESELLSCHAFT (DE) 1980-05-20 US disclosed
US-4191686-A FROM SULFONYL HALIDE SUBSTITUTED PARENT BY AMIDATION WITH AROMATIC DIAMINE, DIAZOTIZING, COUPLING TO KETO SUCCINIC ESTER, CYCLIZING, COUPLING TO REACTIVE MOIETY CASSELLA AKTIENGESELLSCHAFT (DE) 1980-03-04 US disclosed
US-4191687-A Reactive dyestuffs containing the residue of 1-hydroxy-7-amino-8-(5'-amino-2',4'-disulphophenylazo)naphthalene-3,6-disulphonic acid IMPERIAL CHEMICAL INDUSTRIES LIMITED (GB) 1980-03-04 US disclosed
EP-0001451-A1 Water-soluble azo-phthalocyanine fibre-reactive dyestuffs, their preparation and their use CASSELLA Aktiengesellschaft (DE) 1979-04-18 EP disclosed