Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ALDH1A1 | P00352 | 5/20 | 0.45 |
| ▸ | TSHR | P16473 | 6/20 | 0.41 |
| ▸ | HSD17B10 | Q99714 | 4/20 | 0.41 |
| ▸ | CYP3A4 | P08684 | 4/20 | 0.41 |
| ▸ | RECQL | P46063 | 3/20 | 0.41 |
| ▸ | NOTUM | Q6P988 | 2/20 | 0.39 |
| ▸ | HPGD | P15428 | 3/20 | 0.36 |
| ▸ | AHR | P35869 | 2/20 | 0.36 |
| ▸ | TP53 | P04637 | 2/20 | 0.35 |
| ▸ | MAPK1 | P28482 | 3/20 | 0.33 |
| ▸ | TDP1 | Q9NUW8 | 2/20 | 0.33 |
| ▸ | PDK2 | Q15119 | 1/20 | 0.33 |
| ▸ | CES1 | P23141 | 1/20 | 0.32 |
| ▸ | DNMT1 | P26358 | 1/20 | 0.32 |
| ▸ | KDM4E | B2RXH2 | 2/20 | 0.32 |
| ▸ | MEN1 | O00255 | 2/20 | 0.32 |
| ▸ | MAPT | P10636 | 2/20 | 0.32 |
| ▸ | ALOX15 | P16050 | 2/20 | 0.32 |
| ▸ | ALOX12 | P18054 | 2/20 | 0.32 |
| ▸ | CASP1 | P29466 | 2/20 | 0.32 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL25291034 | 0.85 | TSHR (0.46) | ALDH1A1TSHRHSD17B10CYP3A4RECQL | |
| SCHEMBL13550052 | 0.83 | RAPGEF4 (0.39) | ALDH1A1TSHRHSD17B10CYP3A4RECQL | |
| SCHEMBL15850522 | 0.80 | PDE2A (0.41) | ALDH1A1TSHRCYP3A4NOTUMHPGD | |
| SCHEMBL24634001 | 0.78 | NMT1 (0.38) | NOTUM | |
| SCHEMBL22444613 | 0.78 | NOTUM (0.46) | NOTUM | |
| SCHEMBL24633969 | 0.78 | NOTUM (0.37) | NOTUM | |
| SCHEMBL25014091 | 0.78 | CYP3A4 (0.50) | ALDH1A1TSHRHSD17B10CYP3A4RECQL | |
| SCHEMBL21625602 | 0.78 | PTGS1 (0.35) | ALDH1A1TSHRHSD17B10CYP3A4RECQL | |
| SCHEMBL25285782 | 0.78 | ALDH1A1 (0.34) | ALDH1A1TSHRHSD17B10CYP3A4RECQL | |
| Hydrochloric Acid SCHEMBL25373977 | 0.76 | CYP3A4 (0.48) | ALDH1A1TSHRHSD17B10CYP3A4RECQL |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 14 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-118684552-A | Method for direct trifluoromethyl of electron-deficient aromatic ring | 武汉软件工程职业学院(武汉开放大学) | 2024-09-24 | — | — | CN | claimed |
| CN-101891675-B | Production method of 6-chloro-2-(trichloromethyl)pyridine | DONGYANG YINGRUOHUA GREEN ELECTROCHEMISTRY CO LTD OF HENGDIAN GROUP | 2011-12-14 | — | — | CN | claimed |
| CN-101891675-A | Production method of 6-chloro-2-(trichloromethyl)pyridine | DONGYANG YINGRUOHUA GREEN ELECTROCHEMISTRY CO LTD OF HENGDIAN GROUP | 2010-11-24 | — | — | CN | claimed |
| CN-119425752-B | Catalyst for synthesizing chloropyridine and derivative thereof and preparation method thereof | 内蒙古中辉生物科技有限公司 | 2025-05-09 | — | — | CN | disclosed |
| CN-119306658-B | Preparation method of chloropyridine and derivative thereof | 内蒙古中辉生物科技有限公司 | 2025-05-09 | — | — | CN | disclosed |
| CN-119425752-A | Catalyst for synthesizing chloropyridine and derivative thereof and preparation method thereof | 内蒙古中辉生物科技有限公司 | 2025-02-14 | — | — | CN | disclosed |
| CN-119306658-A | Preparation method of chloropyridine and derivative thereof | 内蒙古中辉生物科技有限公司 | 2025-01-14 | — | — | CN | disclosed |
| CN-118684552-A | Method for direct trifluoromethyl of electron-deficient aromatic ring | 武汉软件工程职业学院(武汉开放大学) | 2024-09-24 | — | — | CN | disclosed |
| CN-101891675-B | Production method of 6-chloro-2-(trichloromethyl)pyridine | DONGYANG YINGRUOHUA GREEN ELECTROCHEMISTRY CO LTD OF HENGDIAN GROUP | 2011-12-14 | — | — | CN | disclosed |
| CN-101891675-A | Production method of 6-chloro-2-(trichloromethyl)pyridine | DONGYANG YINGRUOHUA GREEN ELECTROCHEMISTRY CO LTD OF HENGDIAN GROUP | 2010-11-24 | — | — | CN | disclosed |
| EP-0302326-B1 | PROCESS FOR PREPARING FLUORINATED AND OPTIONALLY ALSO CHLORINATED BENZOTRIFLUORIDES, AND BENZOTRIFLUORIDES | BAYER AG (DE) | 1992-04-15 | — | — | EP | disclosed |
| US-4962246-A | INSECTICIDE INTERMEDIATES | BAYER AKTIENGESELLSCHAFT (DE) | 1990-10-09 | — | — | US | disclosed |
| US-4885415-A | HYDROGENATION, DECHLORINATION, CATALYSIS | BAYER AKTIENGESELLSCHAFT (DE) | 1989-12-05 | — | — | US | disclosed |
| EP-0302326-A1 | Process for preparing fluorinated and optionally also chlorinated benzotrifluorides, and benzotrifluorides | BAYER AG (DE) | 1989-02-08 | — | — | EP | disclosed |