Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ALDH1A1 | P00352 | 4/20 | 0.57 |
| ▸ | MAPT | P10636 | 4/20 | 0.57 |
| ▸ | MEN1 | O00255 | 3/20 | 0.57 |
| ▸ | MAPK1 | P28482 | 3/20 | 0.57 |
| ▸ | BLM | P54132 | 3/20 | 0.57 |
| ▸ | KMT2A | Q03164 | 3/20 | 0.57 |
| ▸ | LMNA | P02545 | 2/20 | 0.57 |
| ▸ | TP53 | P04637 | 2/20 | 0.57 |
| ▸ | CYP1A2 | P05177 | 2/20 | 0.57 |
| ▸ | CYP3A4 | P08684 | 2/20 | 0.57 |
| ▸ | HSPD1 | P10809 | 2/20 | 0.57 |
| ▸ | HPGD | P15428 | 2/20 | 0.57 |
| ▸ | CDC25A | P30304 | 2/20 | 0.57 |
| ▸ | CDC25B | P30305 | 2/20 | 0.57 |
| ▸ | HSPE1 | P61604 | 2/20 | 0.57 |
| ▸ | SMN1; SMN2 | Q16637 | 2/20 | 0.57 |
| ▸ | TST | Q16762 | 2/20 | 0.57 |
| ▸ | USP2 | O75604 | 2/20 | 0.57 |
| ▸ | GAA | P10253 | 2/20 | 0.57 |
| ▸ | IDO1 | P14902 | 2/20 | 0.57 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL12819445 | 0.92 | ALDH1A1 (0.57) | ALDH1A1MAPTMEN1MAPK1BLM | |
| SCHEMBL5820386 | 0.80 | ALDH1A1 (0.61) | ALDH1A1MAPTMEN1MAPK1BLM | |
| SCHEMBL28455735 | 0.78 | MAOB (0.39) | ALDH1A1MAPTMEN1MAPK1BLM | |
| SCHEMBL27741769 | 0.78 | ALDH1A1 (0.39) | ALDH1A1MAPTMEN1MAPK1BLM | |
| SCHEMBL31288113 | 0.78 | ALDH1A1 (0.39) | ALDH1A1MAPTMEN1MAPK1BLM | |
| SCHEMBL9627970 | 0.77 | ALDH1A1 (0.57) | ALDH1A1MAPTMEN1MAPK1BLM | |
| SCHEMBL30004118 | 0.77 | ESR1 (0.57) | ALDH1A1MAPTMEN1MAPK1BLM | |
| SCHEMBL11013388 | 0.77 | ESR1 (0.57) | ALDH1A1MAPTMEN1MAPK1BLM | |
| SCHEMBL9628267 | 0.77 | PTPN1 (0.44) | ALDH1A1CYP1A2CYP3A4IDO1PTPN1 | |
| SCHEMBL27492510 | 0.77 | PTPN1 (0.44) | ALDH1A1MAPTMEN1MAPK1KMT2A |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 28 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-20240327328-A1 | PREPARATION OF 6-SUBSTITUTED MENADIONES | UNIVERSITE DE HAUTE ALSACE (FR) | 2024-10-03 | — | — | US | disclosed |
| US-20240174589-A1 | PHOTOREDOX RADICAL BENZYLATION PROCESS | CENTRE NAT RECH SCIENT (FR) | 2024-05-30 | — | — | US | disclosed |
| EP-4370495-A1 | PREPARATION OF 6-SUBSTITUTED MENADIONES | Centre National de la Recherche Scientifique (FR) | 2024-05-22 | — | — | EP | disclosed |
| EP-4347566-A1 | HETEROAROMATIC ANALOGUES OF 3-BENZYLMENADIONE DERIVATIVES AND PROCESSES FOR THEIR PREPARATION | Centre National de la Recherche Scientifique (FR) | 2024-04-10 | — | — | EP | disclosed |
| WO-2023285509-A1 | PREPARATION OF 6-SUBSTITUTED MENADIONES | CENTRE NATIONAL DE LA RECHERCHE SCIENTIFIQUE (FR) | 2023-01-19 | — | — | WO | disclosed |
| WO-2023285509-A1 | PREPARATION OF 6-SUBSTITUTED MENADIONES | CENTRE NATIONAL DE LA RECHERCHE SCIENTIFIQUE (FR) | 2023-01-19 | — | — | WO | disclosed |
| WO-2022254034-A1 | HETEROAROMATIC ANALOGUES OF 3-BENZYLMENADIONE DERIVATIVES AND PROCESSES FOR THEIR PREPARATION | CENTRE NATIONAL DE LA RECHERCHE SCIENTIFIQUE (FR) | 2022-12-08 | — | — | WO | disclosed |
| EP-4053096-A1 | PHOTOREDOX RADICAL BENZYLATION PROCESS | Centre national de la recherche scientifique (FR) | 2022-09-07 | — | — | EP | disclosed |
| EP-2691372-B1 | TOTAL SYNTHESIS OF REDOX-ACTIVE 1.4-NAPHTHOQUINONES AND THEIR METABOLITES AND THEIR THERAPEUTIC USE AS ANTIMALARIAL AND SCHISTOMICIDAL AGENTS | CENTRE NAT RECH SCIENT (FR) | 2019-10-16 | — | — | EP | disclosed |
| EP-2691372-B1 | TOTAL SYNTHESIS OF REDOX-ACTIVE 1.4-NAPHTHOQUINONES AND THEIR METABOLITES AND THEIR THERAPEUTIC USE AS ANTIMALARIAL AND SCHISTOMICIDAL AGENTS | CENTRE NAT RECH SCIENT (FR) | 2019-10-16 | — | — | EP | disclosed |
| WO-2012131010-A1 | TOTAL SYNTHESIS OF REDOX-ACTIVE 1.4-NAPHTHOQUINONES AND THEIR METABOLITES AND THEIR THERAPEUTIC USE AS ANTIMALARIAL AND SCHISTOMICIDAL AGENTS | CENTRE NATIONAL DE LA RECHERCHE SCIENTIFIQUE (FR) | 2012-10-04 | — | — | WO | disclosed |
| EP-2505583-A1 | Total synthesis of redox-active 1.4-naphthoquinones and their metabolites and their therapeutic use as antimalarial and schistomicidal agents | Centre National de la Recherche Scientifique (FR) | 2012-10-03 | — | — | EP | disclosed |
| EP-2505583-A1 | Total synthesis of redox-active 1.4-naphthoquinones and their metabolites and their therapeutic use as antimalarial and schistomicidal agents | Centre National de la Recherche Scientifique (FR) | 2012-10-03 | — | — | EP | disclosed |
| US-5155132-A | Nonsteroidal antiinflammatory agents; treating psoriasis | SYNTEX (U.S.A.) INC. (US) | 1992-10-13 | — | — | US | disclosed |
| US-5134161-A | Enzyme inhibitors for skin disorders, antiinflammatory agents | SYNTEX (U.S.A.) INC. (US) | 1992-07-28 | — | — | US | disclosed |
| US-5089657-A | Topical antiinflammatory agents | SYNTEX (U.S.A.) INC. (US) | 1992-02-18 | — | — | US | disclosed |
| US-4786652-A | TOPICAL ADMINISTRATION | SYNTEX (U.S.A.) INC. (US) | 1988-11-22 | — | — | US | disclosed |
| EP-0282056-A2 | Naphthalene anti-psoriatic agents | SYNTEX (U.S.A.) INC. (US) | 1988-09-14 | — | — | EP | disclosed |
| EP-0282006-A1 | Naphtalene anti-psoriatic agents | SYNTEX (U.S.A.) INC. (US) | 1988-09-14 | — | — | EP | disclosed |
| US-4758587-A | Naphthalene anti-psoriatic agents | SYNTEX (U.S.A.) INC. (US) | 1988-07-19 | — | — | US | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (2 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20240327328-A1 | PREPARATION OF 6-SUBSTITUTED MENADIONES | HSD17B7, CYP17A1, AKR1C4 | ALDH1A1 135/4885MAPT 3505/4885MEN1 14/4885 |
| US-20240174589-A1 | PHOTOREDOX RADICAL BENZYLATION PROCESS | H1-2, H1-3, H1-0 | ALDH1A1 860/4885MAPT 3960/4885MEN1 1297/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.