Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | CDC25A | P30304 | 2/20 | 0.62 |
| ▸ | CDC25B | P30305 | 2/20 | 0.62 |
| ▸ | IDO1 | P14902 | 1/20 | 0.62 |
| ▸ | MAOA | P21397 | 1/20 | 0.50 |
| ▸ | MAOB | P27338 | 1/20 | 0.50 |
| ▸ | ELANE | P08246 | 1/20 | 0.48 |
| ▸ | S100A4 | P26447 | 1/20 | 0.48 |
| ▸ | TDP2 | O95551 | 2/20 | 0.47 |
| ▸ | NSD2 | O96028 | 2/20 | 0.47 |
| ▸ | GAPDH | P04406 | 2/20 | 0.45 |
| ▸ | PTPN1 | P18031 | 1/20 | 0.44 |
| ▸ | HKDC1 | Q2TB90 | 3/20 | 0.44 |
| ▸ | PDE4D | Q08499 | 1/20 | 0.43 |
| ▸ | ALKBH3 | Q96Q83 | 1/20 | 0.41 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.41 |
| ▸ | MEN1 | O00255 | 1/20 | 0.41 |
| ▸ | USP2 | O75604 | 1/20 | 0.41 |
| ▸ | TP53 | P04637 | 1/20 | 0.41 |
| ▸ | CYP3A4 | P08684 | 1/20 | 0.41 |
| ▸ | MAPT | P10636 | 1/20 | 0.41 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL9627801 | 0.93 | CDC25A (0.62) | CDC25ACDC25BIDO1MAOAMAOB | |
| SCHEMBL5809726 | 0.82 | IDO1 (0.62) | CDC25ACDC25BIDO1TDP2NSD2 | |
| SCHEMBL9629332 | 0.81 | CDC25B (0.49) | CDC25ACDC25BIDO1MAOAMAOB | |
| SCHEMBL15026430 | 0.81 | IDO1 (0.61) | CDC25ACDC25BIDO1S100A4TDP2 | |
| SCHEMBL7807732 | 0.81 | IDO1 (0.61) | CDC25ACDC25BIDO1S100A4TDP2 | |
| SCHEMBL30004088 | 0.79 | IDO1 (0.58) | CDC25ACDC25BIDO1S100A4TDP2 | |
| SCHEMBL8582314 | 0.79 | IDO1 (0.58) | CDC25ACDC25BIDO1S100A4TDP2 | |
| SCHEMBL9713496 | 0.79 | IDO1 (0.42) | CDC25ACDC25BIDO1MAOAMAOB | |
| SCHEMBL29291850 | 0.79 | MAOA (0.40) | CDC25ACDC25BIDO1MAOAMAOB | |
| Chimaphilin SCHEMBL30186450 | 0.77 | ALDH1A1 (0.61) | CDC25ACDC25BIDO1MAOAMAOB |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 9 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-5155132-A | Nonsteroidal antiinflammatory agents; treating psoriasis | SYNTEX (U.S.A.) INC. (US) | 1992-10-13 | — | — | US | disclosed |
| US-5134161-A | Enzyme inhibitors for skin disorders, antiinflammatory agents | SYNTEX (U.S.A.) INC. (US) | 1992-07-28 | — | — | US | disclosed |
| US-5089657-A | Topical antiinflammatory agents | SYNTEX (U.S.A.) INC. (US) | 1992-02-18 | — | — | US | disclosed |
| US-5049236-A | Lignin derived quinonic compound mixtures useful for the delignification of cellulosic materials | INSTITUTE OF PAPER SCIENCE AND TECHNOLOGY, INC. (US) | 1991-09-17 | — | — | US | disclosed |
| US-5002634-A | Method for the delignification of wood pulp utilizing fused ring quinone compounds prepared from lignin or lignin derived substances | INSTITUTE OF PAPER SCIENCE AND TECHNOLOGY, INC. (US) | 1991-03-26 | — | — | US | disclosed |
| US-4786652-A | TOPICAL ADMINISTRATION | SYNTEX (U.S.A.) INC. (US) | 1988-11-22 | — | — | US | disclosed |
| EP-0282006-A1 | Naphtalene anti-psoriatic agents | SYNTEX (U.S.A.) INC. (US) | 1988-09-14 | — | — | EP | disclosed |
| EP-0282056-A2 | Naphthalene anti-psoriatic agents | SYNTEX (U.S.A.) INC. (US) | 1988-09-14 | — | — | EP | disclosed |
| US-4758587-A | Naphthalene anti-psoriatic agents | SYNTEX (U.S.A.) INC. (US) | 1988-07-19 | — | — | US | disclosed |