Dimethylamine

Dimethylamine

SCHEMBL9628538

CNC.c1ccc([Al](c2ccccc2)c2ccccc2)cc1

nearest known ligand 0.43

Full drug profile on Sugi Atlas →

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
TSHR P16473 2/20 0.43
KCNN4 O15554 1/20 0.38
KDM4E B2RXH2 2/20 0.36
MAPT P10636 2/20 0.36
CYP3A4 P08684 1/20 0.36
LMNA P02545 2/20 0.35
ALOX12 P18054 1/20 0.35
ACHE P22303 1/20 0.35
APOBEC3A P31941 1/20 0.35
APOBEC3G Q9HC16 1/20 0.35
TAAR1 Q96RJ0 3/20 0.35
ALDH1A1 P00352 2/20 0.35
HSD17B10 Q99714 2/20 0.35
TDP1 Q9NUW8 2/20 0.35
ATM Q13315 1/20 0.35
USP2 O75604 1/20 0.35
POLB P06746 1/20 0.35
HPGD P15428 1/20 0.35
RECQL P46063 1/20 0.35
NPSR1 Q6W5P4 1/20 0.35

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL49939 0.87 ALDH1A1 (0.40) TSHRMAPTLMNAALOX12ACHE
Methylamine SCHEMBL9746311 0.84 LMNA (0.37) TSHRKDM4EMAPTCYP3A4LMNA
Ammonia Solution, Strong SCHEMBL6301069 0.83 ALDH1A1 (0.38) TSHRMAPTLMNAALOX12ACHE
SCHEMBL28105654 0.83 ALDH1A1 (0.38) TSHRMAPTLMNAALOX12ACHE
SCHEMBL31585928 0.83 ALDH1A1 (0.38) TSHRMAPTLMNAALOX12ACHE
Hydrochloric Acid SCHEMBL27449759 0.83 ALDH1A1 (0.38) TSHRMAPTLMNAALOX12ACHE
SCHEMBL28256186 0.81 TSHR (0.35) TSHRKDM4ECYP3A4LMNAALOX12
Hydrochloric Acid SCHEMBL9231122 0.80 ALDH1A1 (0.35) TSHRMAPTLMNAALOX12ACHE
Potassium Ion SCHEMBL29140251 0.80 ALDH1A1 (0.35) TSHRMAPTLMNAALOX12ACHE
Hydrochloric Acid SCHEMBL10587418 0.80 ALDH1A1 (0.35) TSHRKDM4EMAPTLMNAALOX12

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 6 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-5164263-A Aluminum nitride flakes and spheres E. I. DU PONT DE NEMOURS & CO. (US) 1992-11-17 US disclosed
EP-0259164-B1 A MELT-FORMABLE ORGANOALUMINUM POLYMER E.I. DU PONT DE NEMOURS AND COMPANY (US) 1992-05-20 EP disclosed
US-5041512-A Trialkylauminum and dialkylaluminum amide; pyrolysis; aluminum nitride; high density; fibers; ceramics E. I. DU PONT DE NEMOURS AND COMPANY (US) 1991-08-20 US disclosed
US-4908197-A Aluminum nitride flakes and spheres E. I. DU PONT DE NEMOURS AND COMPANY (US) 1990-03-13 US disclosed
EP-0259164-A1 A melt-formable organoaluminum polymer E.I. DU PONT DE NEMOURS AND COMPANY (US) 1988-03-09 EP disclosed
US-4696968-A Melt-formable organoaluminum polymer E. I. DU PONT DE NEMOURS AND COMPANY (US) 1987-09-29 US disclosed