Predicted protein targets (top 3)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | MTNR1A | P48039 | 15/20 | 0.54 |
| ▸ | MTNR1B | P49286 | 16/20 | 0.52 |
| ▸ | NQO2 | P16083 | 10/20 | 0.52 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL1846866 | 0.91 | MTNR1B (0.52) | MTNR1AMTNR1BNQO2 | |
| SCHEMBL1842495 | 0.86 | MTNR1A (0.56) | MTNR1AMTNR1BNQO2 | |
| SCHEMBL19838588 | 0.86 | MTNR1A (0.59) | MTNR1AMTNR1BNQO2 | |
| SCHEMBL30746730 | 0.86 | MTNR1A (0.56) | MTNR1AMTNR1BNQO2 | |
| Hydrochloric Acid SCHEMBL9628615 | 0.85 | MTNR1A (0.54) | MTNR1AMTNR1BNQO2 | |
| SCHEMBL2842735 | 0.85 | MTNR1A (0.58) | MTNR1AMTNR1BNQO2 | |
| SCHEMBL2825083 | 0.85 | MTNR1A (0.54) | MTNR1AMTNR1BNQO2 | |
| SCHEMBL19852377 | 0.82 | MTNR1A (0.55) | MTNR1AMTNR1BNQO2 | |
| SCHEMBL10468373 | 0.82 | MTNR1A (0.55) | MTNR1AMTNR1BNQO2 | |
| SCHEMBL28297098 | 0.82 | MTNR1A (0.52) | MTNR1AMTNR1BNQO2 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 4 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0281261-B1 | 3-AMINOMETHYL DERIVATIVES OF INDANE, INDOLINE AND DIHYDROBENZOFURANE AND DIHYDROBENZOTHIOPHENE | H. LUNDBECK A/S (DK) | 1992-05-06 | — | — | EP | disclosed |
| US-4957914-A | ANTIDEPRESSANTS, ANXIOLYTICS, HYPOTENSIVE AGENTS | SYNTEX (U.S.A.) INC. (US) | 1990-09-18 | — | — | US | disclosed |
| US-4946863-A | CNS-affecting 6-oxy-3-aminomethyl indanes, compositions thereof, and method of treating therewith | H. LUNDBECK A/S (DK) | 1990-08-07 | — | — | US | disclosed |
| US-4847254-A | CNS affecting 5-oxy-3-aminomethyl-dihydro-benzofurans and benzothiophenes | H. LUNDBECK A/S (DK) | 1989-07-11 | — | — | US | disclosed |