Predicted protein targets (top 12)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | LMNA | P02545 | 1/20 | 0.56 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.55 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.54 |
| ▸ | CYP2D6 | P10635 | 1/20 | 0.54 |
| ▸ | CYP2C19 | P33261 | 1/20 | 0.54 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.51 |
| ▸ | POLB | P06746 | 2/20 | 0.47 |
| ▸ | HPGD | P15428 | 1/20 | 0.46 |
| ▸ | HTT | P42858 | 1/20 | 0.46 |
| ▸ | AGTR1 | P30556 | 1/20 | 0.43 |
| ▸ | AGTR2 | P50052 | 1/20 | 0.43 |
| ▸ | FDPS | P14324 | 1/20 | 0.42 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL11013825 | 0.85 | TDP1 (0.51) | LMNATDP1CYP1A2CYP2D6CYP2C19 | |
| SCHEMBL28203075 | 0.82 | MAPT (0.47) | KMT2APOLB | |
| SCHEMBL11289075 | 0.82 | TDP1 (0.51) | LMNATDP1CYP1A2CYP2D6CYP2C19 | |
| SCHEMBL11292990 | 0.80 | TDP1 (0.51) | LMNATDP1CYP1A2CYP2D6CYP2C19 | |
| Hydrochloric Acid SCHEMBL28192690 | 0.79 | LMNA (0.49) | LMNATDP1CYP1A2CYP2D6CYP2C19 | |
| Iodide SCHEMBL29037976 | 0.79 | TDP1 (0.61) | LMNATDP1CYP1A2CYP2D6CYP2C19 | |
| Hydrochloric Acid SCHEMBL28192676 | 0.79 | TDP1 (0.61) | LMNATDP1CYP1A2CYP2D6CYP2C19 | |
| SCHEMBL11291674 | 0.78 | TDP1 (0.55) | LMNATDP1CYP1A2CYP2D6CYP2C19 | |
| SCHEMBL3316613 | 0.78 | LMNA (0.58) | LMNATDP1CYP1A2CYP2D6CYP2C19 | |
| SCHEMBL9728093 | 0.78 | CYP1A2 (0.56) | LMNATDP1CYP1A2CYP2D6CYP2C19 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0316783-B1 | PROCESS FOR THE PREPARATION OF HETERO-AROMATIC KETONES AND ALDEHYDES | BASF Aktiengesellschaft (DE) | 1992-03-18 | — | — | EP | disclosed |
| EP-0316783-A1 | Process for the preparation of hetero-aromatic ketones and aldehydes | BASF Aktiengesellschaft (DE) | 1989-05-24 | — | — | EP | disclosed |