Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ALDH1A1 | P00352 | 3/20 | 0.82 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.82 |
| ▸ | POLB | P06746 | 1/20 | 0.82 |
| ▸ | GAA | P10253 | 1/20 | 0.82 |
| ▸ | MEN1 | O00255 | 2/20 | 0.77 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.77 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.77 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.77 |
| ▸ | PTPN11 | Q06124 | 2/20 | 0.46 |
| ▸ | PTPRO | Q16827 | 1/20 | 0.46 |
| ▸ | BCL2L1 | Q07817 | 1/20 | 0.46 |
| ▸ | MCL1 | Q07820 | 1/20 | 0.46 |
| ▸ | PPARA | Q07869 | 1/20 | 0.45 |
| ▸ | CNR2 | P34972 | 3/20 | 0.43 |
| ▸ | STAT3 | P40763 | 1/20 | 0.41 |
| ▸ | KAT8 | Q9H7Z6 | 2/20 | 0.40 |
| ▸ | NPC1 | O15118 | 1/20 | 0.39 |
| ▸ | JAK2 | O60674 | 1/20 | 0.39 |
| ▸ | RAB9A | P51151 | 1/20 | 0.39 |
| ▸ | PAX8 | Q06710 | 1/20 | 0.39 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL11080174 | 0.99 | ALDH1A1 (0.84) | ALDH1A1KDM4EPOLBGAAMEN1 | |
| SCHEMBL3659209 | 0.95 | ALDH1A1 (0.91) | ALDH1A1KDM4EPOLBGAAMEN1 | |
| SCHEMBL3656127 | 0.95 | ALDH1A1 (0.91) | ALDH1A1KDM4EPOLBGAAMEN1 | |
| SCHEMBL264913 | 0.95 | ALDH1A1 (0.91) | ALDH1A1KDM4EPOLBGAAMEN1 | |
| SCHEMBL3660975 | 0.94 | ALDH1A1 (0.93) | ALDH1A1KDM4EPOLBGAAMEN1 | |
| SCHEMBL10780555 | 0.90 | KMT2A (0.85) | ALDH1A1KDM4EPOLBGAAMEN1 | |
| SCHEMBL267885 | 0.90 | ALDH1A1 (1.00) | ALDH1A1KDM4EPOLBGAAMEN1 | |
| 1-Hexanol SCHEMBL28511495 | 0.90 | SMN1; SMN2 (0.80) | ALDH1A1KDM4EPOLBGAAMEN1 | |
| SCHEMBL10933445 | 0.88 | ALDH1A1 (0.95) | ALDH1A1KDM4EPOLBGAAMEN1 | |
| SCHEMBL11083623 | 0.88 | ALDH1A1 (0.78) | ALDH1A1KDM4EPOLBGAAMEN1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-5166350-A | Process for the manufacture of fluoran compounds | CIBA-GEIGY CORPORATION (US) | 1992-11-24 | — | — | US | disclosed |
| US-4444591-A | AMINO-ANILINOFLUORANS | YAMADA CHEMICAL CO., LTD. (JP) | 1984-04-24 | — | — | US | disclosed |