Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | NQO1 | P15559 | 1/20 | 0.52 |
| ▸ | L3MBTL1 | Q9Y468 | 2/20 | 0.45 |
| ▸ | MAPT | P10636 | 2/20 | 0.45 |
| ▸ | LMNA | P02545 | 1/20 | 0.45 |
| ▸ | ATM | Q13315 | 1/20 | 0.45 |
| ▸ | TSHR | P16473 | 1/20 | 0.44 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.44 |
| ▸ | CYP1A1 | P04798 | 1/20 | 0.41 |
| ▸ | CYP1B1 | Q16678 | 1/20 | 0.41 |
| ▸ | MAOB | P27338 | 1/20 | 0.41 |
| ▸ | LTA4H | P09960 | 2/20 | 0.41 |
| ▸ | EPHX2 | P34913 | 1/20 | 0.40 |
| ▸ | NR1H4 | Q96RI1 | 1/20 | 0.40 |
| ▸ | KIF11 | P52732 | 1/20 | 0.40 |
| ▸ | PLK1 | P53350 | 1/20 | 0.40 |
| ▸ | TP53 | P04637 | 1/20 | 0.39 |
| ▸ | GAA | P10253 | 1/20 | 0.39 |
| ▸ | PARP10 | Q53GL7 | 1/20 | 0.38 |
| ▸ | RELA | Q04206 | 1/20 | 0.38 |
| ▸ | CA12 | O43570 | 1/20 | 0.38 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL7934924 | 0.86 | LTA4H (0.44) | TSHRMAOBLTA4HCA12CA1 | |
| SCHEMBL18417195 | 0.81 | NQO1 (0.56) | NQO1L3MBTL1MAPTLMNAATM | |
| SCHEMBL12883936 | 0.80 | NQO1 (0.61) | NQO1L3MBTL1MAPTLMNAATM | |
| SCHEMBL635142 | 0.80 | NQO1 (0.61) | NQO1L3MBTL1MAPTLMNAATM | |
| SCHEMBL27274410 | 0.79 | HSD11B1 (0.47) | L3MBTL1MAPTLMNATSHRTDP1 | |
| SCHEMBL8237725 | 0.78 | NQO1 (0.64) | NQO1L3MBTL1MAPTLMNAATM | |
| SCHEMBL2740777 | 0.77 | NQO1 (0.56) | NQO1L3MBTL1MAPTLMNAATM | |
| SCHEMBL799636 | 0.76 | NQO1 (0.67) | NQO1L3MBTL1MAPTLMNAATM | |
| SCHEMBL3035998 | 0.76 | NQO1 (0.67) | NQO1MAPTTSHRTDP1LTA4H | |
| SCHEMBL13311537 | 0.76 | NQO1 (0.67) | NQO1L3MBTL1MAPTLMNAATM |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 4 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-1020449-C | INSECTICIDAL TRIFFLUORMETHYL ALKANE DERIVATIVES | SCHERING AG (DE) | 1993-05-05 | — | — | CN | disclosed |
| EP-0233834-B1 | INSECTICIDAL TRIFLUORMETHYL ALKANE DERIVATIVES | SCHERING AKTIENGESELLSCHAFT (DE) | 1992-04-22 | — | — | EP | disclosed |
| EP-0233834-A1 | Insecticidal trifluormethyl alkane derivatives | SCHERING AKTIENGESELLSCHAFT (DE) | 1987-08-26 | — | — | EP | disclosed |
| CN-87100438-A | insecticidal trifluoromethyl alkane derivatives | — | 1987-08-12 | — | — | CN | disclosed |